CyBase: a database of cyclic protein sequence and structure

被引：137

作者：

Mulvenna, Jason P. ^{[1
]}

Wang, Conan ^{[1
]}

Craik, David J. ^{[1
]}

机构：

[1] Univ Queensland, Inst Mol Biosci, Brisbane, Qld 4072, Australia

来源：

NUCLEIC ACIDS RESEARCH | 2006年 / 34卷

关键词：

D O I：

10.1093/nar/gkj005

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

CyBase is a curated database and information source for backbone-cyclized proteins. The database incorporates naturally occurring cyclic proteins as well as synthetic derivatives, grafted analogues and acyclic permutants. The database provides a centralized repository of information on all aspects of cyclic protein biology and addresses issues pertaining to the management and searching of topologically circular sequences. The database is freely available at http://research.imb.uq.edu.au/cybase.

引用

页码：D192 / D194

页数：3

共 25 条

[1] Thermal, chemical, and enzymatic stability of the cyclotide kalata B1: The importance of the cyclic cystine knot [J].

Colgrave, ML ;

Craik, DJ .

BIOCHEMISTRY, 2004, 43 (20) :5965-5975

[2] Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif [J].

Craik, DJ ;

Daly, NL ;

Bond, T ;

Waine, C .

JOURNAL OF MOLECULAR BIOLOGY, 1999, 294 (05) :1327-1336

[3] Discovery, structure and biological activities of the cyclotides [J].

Craik, DJ ;

Daly, NL ;

Mulvenna, J ;

Plan, MR ;

Trabi, M .

CURRENT PROTEIN & PEPTIDE SCIENCE, 2004, 5 (05) :297-315

[4] Acyclic permutants of naturally occurring cyclic proteins -: Characterization of cystine knot and β-sheet formation in the macrocyclic polypeptide kalata B1 [J].

Daly, NL ;

Craik, DJ .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (25) :19068-19075

[5] The effect of backbone cyclization on the thermodynamics of β-sheet unfolding:: Stability optimization of the PINWW domain [J].

Deechongkit, S ;

Kelly, JW .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (18) :4980-4986

[6] Conjugative pili of IncP plasmids, and the Ti plasmid T pilus are composed of cyclic subunits [J].

Eisenbrandt, R ;

Kalkum, M ;

Lai, EM ;

Lurz, R ;

Kado, CI ;

Lanka, E .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (32) :22548-22555

[7] Circular proteins in plants -: Solution structure of a novel macrocyclic trypsin inhibitor from Momordica cochinchinensis [J].

Felizmenio-Quimio, ME ;

Daly, NL ;

Craik, DJ .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (25) :22875-22882

[8] The KNOTTIN website and database: a new information system dedicated to the knottin scaffold [J].

Gelly, JC ;

Gracy, J ;

Kaas, Q ;

Le-Nguyen, D ;

Heitz, A ;

Chiche, L .

NUCLEIC ACIDS RESEARCH, 2004, 32 :D156-D159

[9] Novel strategies for isolation and characterization of cyclotides:: The discovery of bioactive macrocyclic plant polypeptides in the Violaceae [J].

Göransson, U ;

Svangård, E ;

Claeson, P ;

Bohlin, L .

CURRENT PROTEIN & PEPTIDE SCIENCE, 2004, 5 (05) :317-329

[10] Disulfide mapping of the cyclotide kalata B1 -: Chemical proof of the cyclic cystine knot motif [J].

Göransson, U ;

Craik, DJ .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (48) :48188-48196

← 1 2 3 →