Unusually long target site duplications flanking some of the long terminal repeats of human endogenous retrovirus K in the human genome

被引：7

作者：

Mamedov, IZ ^{[1
]}

Lebedev, YB ^{[1
]}

Sverdlov, ED ^{[1
]}

机构：

[1] Russian Acad Sci, Shemyakin Ovchinnikov Inst Bioorgan Chem, Moscow 117997, Russia

来源：

JOURNAL OF GENERAL VIROLOGY | 2004年 / 85卷

关键词：

D O I：

10.1099/vir.0.19717-0

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Human endogenous retroviruses (HERVs) make up a substantial part of the human genome. HERVs and solitary long terminal repeats (solo LTRs) are usually flanked by 4-6 nt short direct repeats through the well-known mechanism of their integration. A number of solo LTRs flanked by unusually long direct repeats were detected in the human genome. These unusual structures might be a product of an alternative virus insertion mechanism.

引用

页码：1485 / 1488

页数：4

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