Vergence disorders in patients with spinocerebellar ataxia 3/Machado-Joseph disease: a synoptophore study

被引：12

作者：

Ohyagi, Y

Yamada, T

Okayama, A

Sakae, N

Yamasaki, T

Ohshima, T

Sakamoto, T

Fujii, N

Kira, J

机构：

[1] Kyushu Univ, Grad Sch Med Sci, Neurol Inst, Dept Neurol,Higashi Ku, Fukuoka 8128582, Japan

[2] Kyushu Univ, Grad Sch Med Sci, Dept Ophthalmol, Fukuoka 8128582, Japan

[3] Iizuka Hosp, Dept Neurol, Iizuka, Fukuoka, Japan

来源：

JOURNAL OF THE NEUROLOGICAL SCIENCES | 2000年 / 173卷 / 02期

关键词：

spinocerebellar ataxia 3/Machado-Joseph disease; vergence; synoptophore;

D O I：

10.1016/S0022-510X(99)00309-3

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Diplopia, a common symptom in spinocerebellar ataxia 3/Machado-Joseph disease (SCA3/MJD) cases, is not always due to asymmetric ophthalmoplegia. We found a Japanese SCA3/MJD family, in which three patients clearly had an impairment of divergence eye movement. We thus quantitatively examined the vergence ranges in eight Japanese SCB3/MJD cases using the synoptophore test. An impairment of the vergence eye movements was found in all patients, and the vergence impairment pattern, but not the ophthalmoplegia pattern, was found to be compatible with the diplopia pattern. The diplopia in SCA3/MJD cases is, therefore, attributed, at least in part, to the impairment of the vergence eye movements. (C) 2000 Elsevier Science B.V. All rights reserved.

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页码：120 / 123

页数：4

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