DNA-binding proteins meet their mismatch

被引：0

作者：

Kundert, Kale ^{[1
]}

Fraser, James S. ^{[2
]}

机构：

[1] Harvard Univ, Wyss Inst Biol Inspired Engn, Boston, MA 02138 USA

[2] Univ Calif San Francisco, Dept Bioengn & Therapeut Sci, San Francisco, CA 94158 USA

来源：

NATURE | 2020年 / 587卷 / 7833期

关键词：

Molecular biology;

D O I：

10.1038/d41586-020-02658-x

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Mismatches are alterations in DNA that prevent the bases on each strand of the double helix from aligning correctly. It emerges that mismatches can bend DNA into favourable conformations for binding by proteins.

引用

页码：199 / 200

页数：2

共 50 条

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