Sentinel node biopsy in patients with multifocal and multicentric breast cancer: A 5-year follow-up

被引：2

作者：

Blanco Saiz, I. ^{[1
]}

Lopez Carballo, M. T. ^{[1
]}

Martinez Fernandez, J. ^{[1
]}

Carrion Maldonado, J. ^{[2
]}

Cabrera Pereira, A. ^{[2
]}

Moral Alvarez, S. ^{[2
]}

Santamaria Giron, L. ^{[2
]}

Cantero Cerquella, F. ^{[2
]}

Lopez Secades, A. ^{[3
]}

Diaz Gonzalez, D. ^{[2
]}

Llaneza Folgueras, A. ^{[2
]}

Aira Delgado, F. J. ^{[1
]}

机构：

[1] Clin Med Nucl Geminis, Gijon, Spain

[2] Hosp Cabuenes, Serv Cirugia Gen, Gijon, Asturias, Spain

[3] Hosp Cabuenes, Serv Radiodiagnost, Gijon, Asturias, Spain

来源：

REVISTA ESPANOLA DE MEDICINA NUCLEAR E IMAGEN MOLECULAR | 2014年 / 33卷 / 04期

关键词：

Sentinel lymph node biopsy; Multifocal breast cancer; Multicentric breast cancer; Periareolar injection; LYMPH-NODE; SUBAREOLAR INJECTION; EXPERIENCE; ACCURACY; DRAINAGE; SURGERY; ANATOMY; DISEASE; TRACER; TUMOR;

D O I：

10.1016/j.remn.2013.10.010

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Objective: Sentinel lymph node biopsy (SLNB) as a staging procedure in multiple breast cancer is a controversial issue. We have aimed to evaluate the efficacy of sentinel node (SN) detection in patients with multifocal or multicentric breast cancer as well as the safety of its clinical application after a long follow-up. Material and methods: A prospective descriptive study was performed. Eighty-nine patients diagnosed of multiple breast cancer (73 multifocal; 16 multicentric) underwent SLNB. These patients were compared to those with unifocal neoplasia. Periareolar radiocolloid administration was performed in most of the patients. Evaluation was made at an average of 67.2 months of follow-up (32-126 months). Results: Scintigraphic and surgical SN localization in patients with multiple breast cancer were 95.5% and 92.1%, respectively. A higher percentage of extra-axillary nodes was observed than in the unifocal group (11.7% vs 5.4%) as well as a significantly higher number of SN per patient (1.70 vs 1.38). The rate of SN localization in multicentric cancer was slightly lower than in multifocal cancer (87.5% vs 93.1%), and the finding of extra-axillary drainages was higher (20% vs 10%). Number of SN per patient was significantly higher in multicentric breast cancer (2.33 vs 1.57). No axillary relapses have been demonstrated in the follow-up in multiple breast cancer patients group. Conclusions: SLNB performed by periareolar injection is a reliable and accurate staging procedure of patients with multiple breast cancer, including those with multicentric processes. (C) 2013 Elsevier Espana, S.L. and SEMNIM. All rights reserved.

引用

页码：199 / 204

页数：6

共 30 条

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