Ce/SiO2 composite as an efficient catalyst for the multicomponent one-pot synthesis of substituted pyrazolones in aqueous media and their antimicrobial activities

被引：22

作者：

Akondi, Adinarayana Murthy ^{[1
]}

Kantam, Mannepalli Lakshmi ^{[1
,2
]}

Trivedi, Rajiv ^{[1
]}

Bharatam, Jagadeesh ^{[3
]}

Vemulapalli, Sahitha Phani Babu ^{[3
]}

Bhargava, Suresh K. ^{[4
,5
]}

Buddana, Sudheer Kumar ^{[6
]}

Prakasham, Reddy Shetty ^{[6
]}

机构：

[1] CSIR Indian Inst Chem Technol, Inorgan & Phys Chem Div, Hyderabad 500007, Andhra Pradesh, India

[2] Tezpur Univ, Dept Chem Sci, Napaam 784028, Assam, India

[3] CSIR Indian Inst Chem Technol, Ctr NMR & Struct Chem, Hyderabad 500007, Andhra Pradesh, India

[4] CSIR Indian Inst Chem Technol, RMIT IICT Res Ctr, Hyderabad 500007, Andhra Pradesh, India

[5] RMIT Univ, Sch Appl Sci, Adv Mat & Ind Chem Grp, Melbourne, Vic, Australia

[6] CSIR Indian Inst Chem Technol, Bioengn & Environm Sci, Hyderabad 500007, Andhra Pradesh, India

来源：

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 2016年 / 411卷

关键词：

Ce-SiO2; catalyst; One-pot synthesis; Aqueous media; Substituted pyrazolones; Antimicrobial activity; LEWIS-ACID CATALYSTS; SOLVENT-FREE; BIOLOGICAL EVALUATION; DOMINO REACTIONS; DERIVATIVES; OXIDATION; PERFORMANCE; MANNICH; CERIUM; WATER;

D O I：

10.1016/j.molcata.2015.11.004

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

We describe here the preparation and characterization of a Ce/SiO2 catalyst and its application in an eco-friendly and convenient synthesis of pyrazolone derivatives via one-pot multicomponent reaction of 2-naphthol, aldehydes, phenylhydrazine and ethyl acetoacetate under aqueous media. The catalyst was prepared using sol-gel method and characterized by XRD, XPS, UV-DRS, SEM, TEM and surface area analysis. 2D NMR technique was utilized to ascertain the pyrazolone tautomer. The new compounds were evaluated for anti-microbial activity and exhibited good to promising activity against most of the tested bacterial and fungal strains. (C) 2015 Elsevier B.V. All rights reserved.

引用

页码：325 / 336

页数：12

共 54 条

[51] Generation of acid sites on silica-supported rare earth oxide catalysts:: Structural characterization and catalysis for α-pinene isomerization [J].