Guidelines for living donor kidney transplantation

被引:0
作者
Frutos, Miguel Angel [1 ]
Crespo, Marta [2 ]
de la Oliva Valentin, Maria [3 ]
Alonso-Melgar, Angel [4 ]
Alonso, Juana [1 ]
Fernandez, Constantino [5 ]
Garcia-Erauzkin, Gorka [6 ]
Gonzalez, Esther [7 ]
Gonzalez-Rinne, Ana M. [8 ]
Guirado, Lluis [9 ]
Gutierrez-Dalmau, Alex [10 ]
Huguet, Jorge [11 ]
Lopez del Moral, Jose Luis [12 ]
Musquera, Mireia [13 ]
Paredes, David [14 ]
Redondo, Dolores [2 ]
Revuelta, Ignacio [15 ]
Van-der Hofstadt, Carlos J. [16 ]
Alcaraz, Antonio [13 ]
Alonso-Hernandez, Angel [5 ]
Alonso, Manuel [17 ]
Bernabeu, Purificacion [16 ]
Bernal, Gabriel [18 ]
Breda, Alberto [11 ]
Cabello, Mercedes [1 ]
Luis Caro-Oleas, Jose [19 ]
Cid, Joan [20 ]
Diekmann, Fritz [15 ]
Espinosa, Laura [4 ]
Facundo, Carme [9 ]
Garcia, Marta [3 ]
Gil-Vernet, Salvador [21 ]
Lozano, Miquel [20 ]
Mahillo, Beatriz [3 ]
Jose Martinez, Maria [22 ]
Miranda, Blanca [23 ]
Oppenheimer, Federico [15 ]
Palou, Eduard [19 ]
Jose Perez-Saez, Maria [2 ]
Peri, Lluis [13 ]
Rodriguez, Oscar [11 ]
Santiago, Carlos [24 ]
Tabernero, Guadalupe [25 ]
Hernandez, Domingo [1 ]
Dominguez-Gil, Beatriz [3 ]
Pascual, Julio [2 ]
机构
[1] Hosp Reg Univ Malaga, Serv Nefrol, Malaga, Spain
[2] Hosp Mar, Serv Nefrol, Barcelona, Spain
[3] Org Nacl Trasplantes, Madrid, Spain
[4] Hosp La Paz, Serv Nefrol Pediat, Madrid, Spain
[5] Hosp Univ A Coruna, Serv Nefrol, La Coruna, Spain
[6] Hosp Univ Cruces, Serv Nefrol, Bilbao, Spain
[7] Hosp Univ 12 Octubre, Serv Nefrol, Madrid, Spain
[8] Hosp Univ Canarias, Serv Nefrol, Santa Cruz De Tenerife, Spain
[9] Fundacio Puigvert, Serv Nefrol, Barcelona, Spain
[10] Hosp Univ Miguel Seruet, Serv Nefrol, Zaragoza, Spain
[11] Fundacio Puigvert, Equipo Quirurg TR, Barcelona, Spain
[12] Magistrado Tribunal Super Justicia Cantabria, Cantabria, Spain
[13] Hosp Clin Univ, Serv Urol, Barcelona, Spain
[14] Hosp Clin Univ, Secc Donac & Coordinac Trasplantes, Barcelona, Spain
[15] Hosp Clin Univ, Serv Nefrol & TR, Barcelona, Spain
[16] Hosp Gen Univ Alicante, Unidad Psicol Hosp, Alicante, Spain
[17] Coordinac Autonom Trasplantes, Seville, Spain
[18] Hosp Univ Virgen Rocio, Serv Nefrol, Seville, Spain
[19] Hosp Clin & Univ, Serv Inmunol, Barcelona, Spain
[20] Hosp Clin Univ, Serv Hemoterapia & Hemostasia, Unidad Aferesis & Terapia Celular, Barcelona, Spain
[21] Hosp Univ Bellvitge, Serv Nefrol, Barcelona, Spain
[22] Hosp Univ La Paz, Serv Urol Pediat, Madrid, Spain
[23] Fdn Renal Inigo Alvarez Toledo, Madrid, Spain
[24] Hosp Gen Alicante, Serv Nefrol, Alicante, Spain
[25] Hosp Univ Salamanca, Serv Nefrol, Salamanca, Spain
来源
NEFROLOGIA | 2022年 / 42卷
关键词
GLOMERULAR-FILTRATION-RATE; RABBIT ANTITHYMOCYTE GLOBULIN; INCOMPATIBLE RENAL-TRANSPLANTATION; ANTIGEN-SPECIFIC IMMUNOADSORPTION; ANTIBODY-MEDIATED REJECTION; POSITIVE CROSS-MATCH; TERM-FOLLOW-UP; ANTILYMPHOCYTE INDUCTION THERAPY; COATED MYCOPHENOLATE SODIUM; INTRAVENOUS IMMUNE GLOBULIN;
D O I
10.1016/j.nefro.2021.10.002
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
This guide for living donor renal transplantation (LDRT) has been prepared with the sponsorship of the Spanish Society of Nephrology (SEN), the Spanish Transplant Society (SET), and the Spanish National Transplant Organization (ONT). It updates evidence to offer the best chronic renal failure treatment when a potential living donor is available. The core aim of this guide is to supply clinicians who evaluate living donors and transplant recipients with the best decision-making tools, to optimise their outcomes. Moreover, the role of living donors in the current RT context should recover the level of importance it had until recently. To this end the new forms of incompatible HLA and/or ABO donation, as well as the paired donation which is possible in several hospitals with experience in LDRT, offer additional ways to treat renal patients with an incompatible donor. Good results in terms of patient and graft survival have expanded the range of circumstances under which living renal donors are accepted. Older donors are now accepted, as are others with factors that affect the decision, such as a borderline clinical history or alterations, which when evaluated may lead to an additional number of transplantations. This guide does not forget that LDRT may lead to risk for the donor. Pre-donation evaluation has to centre on the problems which may arise over the short or long-term, and these have to be described to the potential donor so that they are able to take them into account. Experience over recent years has led to progress in risk analysis, to protect donors' health. This aspect always has to be taken into account by LDRT programmes when evaluating potential donors. Finally, this guide has been designed to aid decision-making, with recommendations and suggestions when uncertainties arise in pre-donation studies. Its overarching aim is to ensure that informed consent is based on high quality studies and information supplied to donors and recipients, offering the strongest possible guarantees. (C) 2021 Published by Elsevier Espana, S.L.U. on behalf of Sociedad Espanola de Nefrologia.
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页码:1 / 128
页数:128
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