Birth cohorts in asthma and allergic diseases: Report of a NIAID/NHLBI/MeDALL joint workshop

被引:78
作者
Bousquet, Jean [1 ,2 ]
Gern, James E. [3 ]
Martinez, Fernando D. [4 ]
Anto, Josep M. [5 ,6 ,7 ,8 ]
Johnson, Christine C. [9 ]
Holt, Patrick G. [10 ,11 ]
Lemanske, Robert F., Jr. [3 ]
Le Souef, Peter N. [12 ]
Tepper, Robert S. [13 ]
von Mutius, Erika R. M. [14 ]
Arshad, S. Hasan [15 ,16 ]
Bacharier, Leonard B. [17 ,18 ]
Becker, Allan [19 ]
Belanger, Kathleen [20 ]
Bergstrom, Anna [21 ]
Bernstein, David I. [22 ]
Cabana, Michael D. [23 ,24 ]
Carroll, Kecia N. [25 ]
Castro, Mario [26 ]
Cooper, Philip J. [27 ,28 ]
Gillman, Matthew W. [29 ]
Gold, Diane R. [30 ,31 ]
Henderson, John [32 ]
Heinrich, Joachim [33 ]
Hong, Soo-Jong [34 ]
Jackson, Daniel J. [3 ]
Keil, Thomas [35 ,36 ]
Kozyrskyj, Anita L. [37 ]
Carlsen, Karin C. Lodrup [38 ,39 ]
Miller, Rachel L. [40 ,43 ]
Momas, Isabelle [41 ,42 ]
Morgan, Wayne J.
Noel, Patricia [44 ]
Ownby, Dennis R. [45 ]
Pinart, Mariona [5 ,6 ,7 ]
Ryan, Patrick H. [46 ]
Schwaninger, Julie M. [47 ]
Sears, Malcolm R. [48 ]
Simpson, Angela [49 ,50 ]
Smit, Henriette A. [51 ]
Stern, Debra A. [4 ]
Subbarao, Padmaja [52 ]
Valenta, Rudolf [53 ]
Wang, Xiaobin [54 ]
Weiss, Scott T. [55 ]
Wood, Robert [56 ]
Wright, Anne L. [57 ,58 ]
Wright, Rosalind J. [59 ,60 ]
Togias, Alkis [47 ]
Gergen, Peter J. [47 ]
机构
[1] Univ Hosp, Montpellier, France
[2] INSERM, U1018, Villejuif, France
[3] Univ Wisconsin, Sch Med & Publ Hlth, Madison, WI 53706 USA
[4] Univ Arizona, Arizona Resp Ctr, Tucson, AZ USA
[5] CREAL, Barcelona, Spain
[6] IMIM Hosp del Mar Res Inst, Barcelona, Spain
[7] CIBERESP, Barcelona, Spain
[8] Univ Pompeu Fabra, Dept Ciencies Expt & Salut, Barcelona, Spain
[9] Henry Ford Hlth Syst, Dept Publ Hlth Sci, Detroit, MI USA
[10] Univ Western Australia, Telethon Inst Child Hlth Res, Brisbane, Qld, Australia
[11] Univ Queensland, Queensland Childrens Med Res Inst, Brisbane, Qld, Australia
[12] Univ Western Australia, Princess Margaret Hosp Children, Sch Paediat & Child Hlth, Perth, WA 6009, Australia
[13] Indiana Univ Sch Med, James Whitcomb Riley Hosp Children, Indianapolis, IN 46202 USA
[14] Univ Munich, Dr von Hauner Childrens Hosp, D-81377 Munich, Germany
[15] Univ Southampton, Fac Med, Isle Of Wight, England
[16] David Hide Asthma & Allergy Res Ctr, Isle Of Wight, England
[17] Washington Univ, St Louis, MO 63130 USA
[18] St Louis Childrens Hosp, St Louis, MO USA
[19] Univ Manitoba, Dept Pediat & Child Hlth, Winnipeg, MB R3T 2N2, Canada
[20] Yale Univ, Sch Publ Hlth, Sch Med, Ctr Perinatal Pediat & Environm Epidemiol, New Haven, CT USA
[21] Karolinska Inst, Inst Environm Med, S-10401 Stockholm, Sweden
[22] Univ Cincinnati, Coll Med, Div Immunol Allergy & Rheumatol, Cincinnati, OH 45221 USA
[23] Univ Calif San Francisco, Dept Pediat, San Francisco, CA USA
[24] Univ Calif San Francisco, Dept Epidemiol & Biostat, San Francisco, CA 94143 USA
[25] Vanderbilt Univ, Med Ctr, Dept Pediat, Nashville, TN 37232 USA
[26] Washington Univ, Sch Med, Div Pulm & Crit Care Med, St Louis, MO 63130 USA
[27] Univ Liverpool, Liverpool Sch Trop Med, Liverpool L3 5QA, Merseyside, England
[28] Pontificia Univ Catolica Ecuador, Escuela Biol, Quito, Ecuador
[29] Harvard Univ, Sch Med, Harvard Pilgrim Hlth Care Inst, Dept Populat Med, Boston, MA USA
[30] Harvard Univ, Brigham & Womens Hosp, Sch Med, Channing Div Network Med,Dept Med, Boston, MA 02115 USA
[31] Harvard Univ, Sch Publ Hlth, Dept Environm Hlth, Boston, MA 02115 USA
[32] Univ Bristol, Sch Social & Community Med, Bristol BS8 1TH, Avon, England
[33] German Ctr Environm Hlth, Helmholtz Zentrum, Inst Epidemiol 1, Munich, Germany
[34] Univ Ulsan, Coll Med, Asan Med Ctr,Dept Pediat, Res Ctr Standardizat Allerg Dis,Childhood Asthma, Seoul, South Korea
[35] Charite, Inst Social Med Epidemiol & Hlth Econ, D-13353 Berlin, Germany
[36] Univ Wurzburg, Inst Clin Epidemiol & Biometry, Wurzburg, Germany
[37] Univ Alberta, Dept Pediat, Fac Med & Dent, Edmonton, AB, Canada
[38] Oslo Univ Hosp, Oslo, Norway
[39] Univ Oslo, N-0316 Oslo, Norway
[40] Columbia Univ, Dept Med, Div Pulm Allergy & Critcare Med, New York, NY USA
[41] Paris Descartes Univ, Dept Publ Hlth & Biostat, Paris, France
[42] Paris Municipal Dept Social Act Childhood & Hlth, Paris, France
[43] Univ Arizona, Dept Pediat, Tucson, AZ 85721 USA
[44] NHLBI, Div Lung Dis, NIH, Bethesda, MD 20892 USA
[45] Georgia Regents Univ, Augusta, GA USA
[46] Cincinnati Childrens Hosp Med Ctr, Div Biostat & Epidemiol, Cincinnati, OH 45229 USA
[47] NIAID, Div Allergy Immunol & Transplantat, NIH, Bethesda, MD 20892 USA
[48] McMaster Univ, AstraZeneca Chair Resp Epidemiol, Dept Med, Hamilton, ON L8S 4L8, Canada
[49] Univ Manchester, Manchester Acad Hlth Sci Ctr, Ctr Resp & Allergy, Inst Inflammat & Repair, Manchester M13 9PL, Lancs, England
[50] Univ Hosp South Manchester, Manchester, Lancs, England
关键词
Allergy; asthma; birth cohorts; National Heart; Lung; and Blood Institute (NHLBI); National Institute of Allergy and Infectious Disease (NIAID); Mechanisms of the Development of Allergy (MeDALL); EXHALED NITRIC-OXIDE; WHEEZING RHINOVIRUS ILLNESSES; 1ST; 6; YEARS; LUNG-FUNCTION; EARLY-LIFE; AIRWAY RESPONSIVENESS; CHILDHOOD ASTHMA; YOUNG-CHILDREN; BRONCHODILATOR RESPONSIVENESS; PRESCHOOL-CHILDREN;
D O I
10.1016/j.jaci.2014.01.018
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Population-based birth cohorts on asthma and allergies increasingly provide new insights into the development and natural history of the diseases. More than 130 birth cohorts focusing on asthma and allergy have been initiated in the last 30 years. A National Institute of Allergy and Infectious Diseases; National Heart, Lung, and Blood Institute; Mechanisms of the Development of Allergy (MeDALL; Framework Programme 7 of the European Commission) joint workshop was held in Bethesda, Maryland, on September 11-12, 2012, with 3 objectives: (1) documenting the knowledge that asthma/allergy birth cohorts have provided, (2) identifying the knowledge gaps and inconsistencies, and (3) developing strategies for moving forward, including potential new study designs and the harmonization of existing asthma birth cohort data. The meeting was organized around the presentations of 5 distinct workgroups: (1) clinical phenotypes, (2) risk factors, (3) immune development of asthma and allergy, (4) pulmonary development, and (5) harmonization of existing birth cohorts. This article presents the workgroup reports and provides Web links (AsthmaBirthCohorts.niaid.nih.gov or www.medall-fp7.eu), where the reader will find tables describing the characteristics of the birth cohorts included in this report, the type of data collected at differing ages, and a selected bibliography provided by the participating birth cohorts.
引用
收藏
页码:1535 / 1546
页数:12
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