Pharmacological evidences for the extracts and secondary metabolites from plants of the genus Hibiscus

被引：89

作者：

Maganha, Elemar Gomes ^{[1
,2
]}

Halmenschlager, Rafael da Costa ^{[3
]}

Rosa, Renato Moreira ^{[1
,2
]}

Pegas Henriques, Joao Antonio ^{[1
,2
,3
]}

Lia de Paula Ramos, Ana Ligia ^{[3
]}

Saffi, Jenifer ^{[1
,2
,3
]}

机构：

[1] Univ Luterana Brasil, Lab Genet Toxicol, BR-92425900 Canoas, RS, Brazil

[2] Univ Luterana Brasil, Programa Posgrad Genet & Toxicol Aplicada, BR-92425900 Canoas, RS, Brazil

[3] Univ Fed Rio Grande do Sul, Dept Biofis, Inst Biociencias, Porto Alegre, RS, Brazil

来源：

FOOD CHEMISTRY | 2010年 / 118卷 / 01期

关键词：

Hibiscus; Phytotherapics; Antioxidants; Medicinal plants; RAT PRIMARY HEPATOCYTES; ROSA-SINENSIS EXTRACT; ABERRANT CRYPT FOCI; PROTOCATECHUIC ACID; SABDARIFFA L; OXIDATIVE STRESS; IN-VITRO; AQUEOUS EXTRACTS; BASELLA-ALBA; DICLIPTERA-VERTICILLATA;

D O I：

10.1016/j.foodchem.2009.04.005

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The scientific basis for the statement that plants and their active constituents play an important role in the prevention of chronic and degenerative diseases is continuously advancing. In fact. the origin of many therapeutic substances is due to secondary metabolism in the plant. The genus Hibiscus contains 220 species distributed around the world. It is an interesting source of potential bioactive molecules, as phenolic compounds, triterpene derivatives, phytosteroids, with antioxidant, cardioprotective, antihypertensive and antiproliferative activities. This work reviews the pharmacological evidence of extracts of plants from the genus Hibiscus, giving an overview of the most studied biological effects and the known phytochemical composition. Although more studies are necessary, Hibiscus spp. exhibits proven potential to become of important pharmacological interest. (C) 2009 Published by Elsevier Ltd.

引用

页码：1 / 10

页数：10

共 106 条

[1]

Adegunloye B J, 1996, Afr J Med Med Sci, V25, P235

[2] Anticlastogenic effects of Hibiscus sabdariffa fruits against sodium arsenite-induced micronuclei formation in erythrocytes in mouse bone marrow [J].

Adetutu, A ;

Odunola, OA ;

Owoade, OA ;

Adeleke, OA ;

Amuda, OS .

PHYTOTHERAPY RESEARCH, 2004, 18 (10) :862-864

[3] In vivo and in vitro evaluation of hair growth potential of Hibiscus rosa-sinensis Linn [J].

Adhirajan, N ;

Kumar, TR ;

Shanmugasundaram, N ;

Babu, M .

JOURNAL OF ETHNOPHARMACOLOGY, 2003, 88 (2-3) :235-239

[4] Mechanisms of the anti-hypertensive effect of Hibiscus sadariffa L. calyces [J].

Ajay, M. ;

Chai, H. J. ;

Mustafa, A. M. ;

Gilani, A. H. ;

Mustafa, M. R. .

JOURNAL OF ETHNOPHARMACOLOGY, 2007, 109 (03) :388-393

[5] The effect of a water extract and anthocyanins of Hibiscus sabdariffa L. on paracetamol-induced hepatoxicity in rats [J].

Ali, BH ;

Mousa, HM ;

El-Mougy, S .

PHYTOTHERAPY RESEARCH, 2003, 17 (01) :56-59

[6]

ALI BH, 2005, PHYTOTHERAPY RES PTR, P75

[7] INVESTIGATION OF THE ANTISPASMODIC POTENTIAL OF HIBISCUS-SABDARIFFA CALYXES [J].

ALI, MB ;

SALIH, WM ;

MOHAMED, AH ;

HOMEIDA, AM .

JOURNAL OF ETHNOPHARMACOLOGY, 1991, 31 (02) :249-257

[8] O6-alkylguanine-DNA alkyltransferase:: influence on susceptibility to the genetic effects of alkylating agents [J].

Kyrtopoulos, SA .

TOXICOLOGY LETTERS, 1998, 103 :53-57

[9] The prevention of cancer [J].

Ames, BN ;

Gold, LS .

DRUG METABOLISM REVIEWS, 1998, 30 (02) :201-223

[10] Effects of Roselle and Ginger on cisplatin-induced reproductive toxicity in rats [J].

Amin, Amr ;

Hamza, AlaaEldin A. .

ASIAN JOURNAL OF ANDROLOGY, 2006, 8 (05) :607-612

← 1 2 3 4 5 6 7 8 9 10 →