Bacteriophage in-feed application: A novel approach to preventing Salmonella Enteritidis colonization in chicks fed experimentally contaminated feed

被引：16

作者：

Kimminau, E. A. ^{[1
]}

Russo, K. N. ^{[1
]}

Karnezos, T. P. ^{[1
]}

Oh, H. G. ^{[2
]}

Lee, J. J. ^{[2
]}

Tate, C. C. ^{[3
]}

Baxter, J. A. ^{[3
]}

Berghaus, R. D. ^{[4
]}

Hofacre, C. L. ^{[3
]}

机构：

[1] Purina Anim Nutr, Gray Summit, MO 63039 USA

[2] CTC Bio, Seoul, South Korea

[3] Southern Poultry Res Grp, Athens, GA USA

[4] Univ Georgia, Coll Vet Med, Dept Populat Hlth, Athens, GA USA

来源：

JOURNAL OF APPLIED POULTRY RESEARCH | 2020年 / 29卷 / 04期

关键词：

Salmonella; feed additive; bacteriophage; ABF; food safety; REDUCE SALMONELLA; COMPETITIVE-EXCLUSION; EGG QUALITY; THERAPY; SUPPLEMENTATION; POULTRY; PERFORMANCE; SKIN; LIVE;

D O I：

10.1016/j.japr.2020.09.003

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

Ensuring the safety of food sources continues to be a priority in animal production. This requires elucidating and utilizing interventions such as bacteriophages (BP) to reduce pathogens such as Salmonella. This study was conducted to evaluate the efficacy of a bacteriophage in the feed for its ability to reduce Salmonella Enteritidis (S.E.) colonization in broilers. Two hundred seventy day-of-hatch broiler chicks were placed into 3 treatments: 1) challenged control, 2) 1 kg BP/metric ton, and 3) 1.5 kg BP/metric ton. Birds were given S.E.contaminated (10(5) CFU/g feed) diets from day of trial (DOT) 8 to 14. Both BP treatments significantly reduced S.E. prevalence from cloacal swabs on DOT 14 (P < 0.001). There were no significant differences in liver and spleen S.E. prevalence among treatments on DOT 28. The S.E. prevalence in the ceca was significantly lower (P < 0.001) in both BP treatments on DOT 28. This study demonstrates the efficacy of in-feed BP in reducing S.E.-contamination of feed as it passes the GI tract.

引用

页码：930 / 936

页数：7

共 42 条

[1] Effect of dietary bacteriophage supplementation on internal organs, fecal excretion, and ileal immune response in laying hens challenged by Salmonella Enteritidis [J].