Intercellular miscommunication in polyglutamine pathogenesis

被引：4
|
作者：
Ross, Christopher A.
Cleveland, Don W.
机构：
[1] Johns Hopkins Univ, Sch Med, Dept Psychiat, Div Neurobiol, Baltimore, MD 21287 USA
[2] Univ Calif San Diego, Ludwig Inst, Dept Neurosci, La Jolla, CA 92093 USA
来源：
NATURE NEUROSCIENCE | 2006年 / 9卷 / 10期
关键词：
D O I：
10.1038/nn1006-1205
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
A new paper demonstrates that polyglutamine pathogenesis in spinocerebellar ataxia need not be cell autonomous. Mutant ataxin-7 expression restricted to Bergmann glia was sufficient to cause Purkinje cell degeneration and neuronal pathology.
引用
收藏
页码：1205 / 1206
页数：2
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