Berberine: A Traditional Natural Product With Novel Biological Activities

被引：2
作者：
Hou, Qian [1 ]
He, Wen-Jun [1 ]
Wu, Yu-Sheng [2 ]
Hao, Hao-Jie [1 ]
Xie, Xiao-Ye [1 ]
Fu, Xiao-Bing [1 ]
机构：
[1] Gen Hosp Peoples Liberat Army, Inst Basic Med, Beijing, Peoples R China
[2] Shandong Univ, Sch Med, Jinan, Shandong, Peoples R China
来源：
ALTERNATIVE THERAPIES IN HEALTH AND MEDICINE | 2020年 / 26卷
基金：
中国博士后科学基金; 国家重点研发计划; 中国国家自然科学基金;
关键词：
CELL-CYCLE ARREST; DOWN-REGULATION; INSULIN-RESISTANCE; CANCER CELLS; IN-VITRO; EMMPRIN EXPRESSION; SIGNALING PATHWAY; MESANGIAL CELLS; AP-1; ACTIVITY; INDUCED MMP-9;
D O I：
暂无
中图分类号：
R [医药、卫生];
学科分类号：
10 ;
摘要：
Context . Having been used for thousands of years to treat gastrointestinal diseases, the natural isoquinoline alkaloid, berberine, has exhibited a wide spectrum of biochemical and pharmacological effects in studies of recent years. Objective . The review intended to examine the many novel bioactivities of berberine, including antidiabetic, anticancer, neuroprotective, anti-inflammatory, and anti-atherosclerotic actions. Design . The research team searched the MEDLINE database using PubMed, using different keyword combinations, including berberine AND diabetes, berberine AND cancer, berberine AND (neuron OR brain), berberine AND inflammation, and "berberine AND atherosclerosis to find studies evaluating the various effects exerted berberine. Conclusion . Berberine is a promising multipotent agent to combat diabetes, cancer, Alzheimer's disease, and other diseases.
引用
收藏
页码：20 / 27
页数：8
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