Similarity studies of DNA sequences based on a new 2D graphical representation

被引:35
作者
Huang, Guohua [1 ,2 ]
Liao, Bo [1 ]
Li, Yongfan [3 ]
Yu, Yougui
机构
[1] Hunan Univ, Sch Comp & Commun, Changsha 410082, Hunan, Peoples R China
[2] Shaoyang Univ, Dept Math, Shaoyang 422000, Hunan, Peoples R China
[3] Hunan First Normal Coll, Changsha 410002, Hunan, Peoples R China
关键词
DNA sequences; Graphical representation; Sequences comparison; Quantitative measure; CHAOS GAME REPRESENTATION; ENTROPIC PROFILES; CODING REGIONS; CURVE; DISSIMILARITY; FREQUENCIES; NUCLEOTIDE; GENE;
D O I
10.1016/j.bpc.2009.03.013
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
We denoted the four nucleotides, A, T, G and C, as four two-component vectors, and illustrated a nucleotide sequence as a curve in the 2D space by concatenating the vectors representing the nucleotides in the sequence. We studied the similarities among multiple nucleotide sequences by comparing their corresponding curves, with the beta-globin genes from 7 species as an example. Crown Copyright (C) 2009 Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:55 / 59
页数:5
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