Minimally invasive surgery for intracerebral haemorrhage

被引:66
作者
Barnes, Benjamin
Hanley, Daniel F.
Carhuapoma, Juan R. [1 ,2 ,3 ]
机构
[1] Johns Hopkins Univ, Div Neurosci Crit Care, Sch Med, Dept Neurol, Baltimore, MD 21287 USA
[2] Johns Hopkins Univ, Div Neurosci Crit Care, Sch Med, Dept Neurosurg, Baltimore, MD 21287 USA
[3] Johns Hopkins Univ, Div Neurosci Crit Care, Sch Med, Dept Anesthesiol & Crit Care Med, Baltimore, MD 21287 USA
关键词
intracerebral haemorrhage; minimally invasive surgery; MISTIE trial; FRAMELESS STEREOTACTIC ASPIRATION; INITIAL CONSERVATIVE TREATMENT; PLASMINOGEN-ACTIVATOR; INTRAVENTRICULAR HEMORRHAGE; PERIHEMATOMAL EDEMA; CLOT RESOLUTION; THROMBOLYSIS; HEMATOMAS; VOLUME; EVACUATION;
D O I
10.1097/MCC.0000000000000077
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Purpose of reviewSpontaneous intracerebral haemorrhage (ICH) imposes a significant health and economic burden on society. Despite this, ICH remains the only stroke subtype without a definitive treatment. Without a clearly identified and effective treatment for spontaneous ICH, clinical practice varies greatly from aggressive surgery to supportive care alone. This review will discuss the current modalities of treatments for ICH including preliminary experience and investigative efforts to advance the care of these patients.Recent findingsOpen surgery (craniotomy), prothrombotic agents and other therapeutic interventions have failed to significantly improve the outcome of these stroke victims. Recently, the Surgical Trial in Intracerebral Haemorrhage (STICH) II assessed the surgical management of patients with superficial intraparenchymal haematomas with negative results. MISTIE II and other trials of minimally invasive surgery (MIS) have shown promise for improving patient outcomes and a phase III trial started in late 2013.SummaryICH lacks a definitive primary treatment as well as a therapy targeting surrounding perihematomal oedema and associated secondary damage. An ongoing phase III trial using MIS techniques shows promise for providing treatment for these patients.
引用
收藏
页码:148 / 152
页数:5
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