Theranostic nanomedicine for cancer detection and treatment

被引:117
作者
Fan, Zhen [1 ]
Fu, Peter P. [2 ]
Yu, Hongtao [1 ]
Ray, Paresh C. [1 ]
机构
[1] Jackson State Univ, Dept Chem & Biochem, Jackson, MS 39217 USA
[2] US FDA, Div Biochem Toxicol, Natl Ctr Toxicol Res, Jefferson, AR USA
关键词
Circulating tumor cell diagnosis; Combined therapy; Photothermal therapy; Selective cancer treatment; Theranostic nanomedicine; CIRCULATING TUMOR-CELLS; IRON-OXIDE NANOPARTICLES; PHOTOTHERMAL THERAPY; GOLD NANOPARTICLES; METHYLENE-BLUE; TARGETED THERAPY; DRUG-DELIVERY; QUANTUM DOTS; DIAGNOSTICS; RELEASE;
D O I
10.1016/j.jfda.2014.01.001
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Cancer is the second leading cause of death in the USA according to the American Cancer Society. In the past 5 years, "theranostic nanomedicine", for both therapeutics and imaging, has shown to be "the right drug for the right patient at the right moment" to manage deadly cancers. This review article presents an overview of recent developments, mainly from the authors' laboratories, along with potential medical applications for theranostic nanomedicine including basic concepts and critical properties. Finally, we outline the future research direction and possible challenges for theranostic nanomedicine research. Copyright (C) 2014, Food and Drug Administration, Taiwan. Published by Elsevier Taiwan LLC. All rights reserved.
引用
收藏
页码:3 / 17
页数:15
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