Synthesis of 3-acetyl-2-amino-4-pyridone

被引：8
作者：
Dorokhov, VA
Komkov, AV
Sakharov, AM
Bogdanov, VS
机构：
[1] N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 117913 Moscow
来源：
RUSSIAN CHEMICAL BULLETIN | 1996年 / 45卷 / 01期
关键词：
diacetylketene aminal; diphenylboron chelates; dimethylformamide dimethylacetal; intramolecular cyclization; 3-acetyl-2-amino-4-pyridone;
D O I：
10.1007/BF01433755
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A method for synthesizing 3-acetyl-2-amino-4-pyridone has been suggested. The synthesis involves the condensation of dimethylformamide dimethylacetal at the NH2 group of diphenylboron chelate diacetylketene aminal followed by its intramolecular cyclization under the action of NaOMe in MeOH.
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收藏
页码：168 / 170
页数：3
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