Bladder Outlet Obstruction in Painful Bladder Syndrome/Interstitial Cystitis

被引:29
作者
Cameron, Anne P. [1 ]
Gajewski, Jerzy B. [2 ]
机构
[1] Univ Michigan, Dept Urol, Ann Arbor, MI 48109 USA
[2] Dalhousie Univ, Dept Urol, Halifax, NS, Canada
关键词
female; urinary bladder neck obstruction; urodynamics; PRESSURE-FLOW ANALYSIS; IDENTIFYING WOMEN; DIAGNOSIS; SYMPTOMS; MEN; PREVALENCE; PARAMETERS; OVERLAP; AID;
D O I
10.1002/nau.20729
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Aims: Obstructive symptoms such as slow stream, dribbling and straining are often reported by painful bladder syndrome and interstitial cystitis (PBS/IC) patients. Our hypothesis was that some patients with PBS/IC have an associated measurable bladder outlet obstruction (BOO) secondary to dysfunctional voiding and that those patients with more severe PBS/IC are more likely to have BOO. Methods: This is a retrospective chart review of female patients diagnosed with PBS/IC based on the NIDDK research definition. Charts were reviewed for clinical symptom severity, ulcer or non-ulcer PBS/IC on cystoscopy, and pressure-flow urodynamics (UDPF). Patients were excluded if they had a urinary infection at the time of urodynamics or did not meet study entry requirements. The cut-off values of <= 12 ml/sec and >= 25 cm of water was used to define BOO. Results: Of the 231 women: 38 had ulcer PBS/IC and 193 had non-ulcer PBS/IC. MCC was 269 ml in non-ulcer PBS/IC and 200 ml in ulcer PBS/IC (P = 0.006). One hundred eleven women (48%) met criteria for obstruction. MCC was 298 ml in the non-obstructed group and 214 ml in the obstructed group (P < 0.0001). The maximum flow with non-ulcer PBS/IC was 11.0 ml/sec and in ulcer PBS/IC 8.9 ml/sec (P = 0.04) Detrusor pressure at maximum flow was 33.3 cm H2O, in non-ulcer, and 37.4 cm H2O in ulcer PBS/IC (P = 0.01). Conclusions: Forty-eight percent of our PBS/IC patients have BOO, and increasing severity of PBS/IC is associated with higher voiding pressure. Neurourol. Urodynam. 28:944-948, 2009. (C) 2009 Wiley-Liss, Inc.
引用
收藏
页码:944 / 948
页数:5
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