BONE Adiposity and bone accrual-still an established paradigm?

被引:19
作者
Kawai, Masanobu [1 ]
Rosen, Clifford J. [1 ]
机构
[1] Maine Med Ctr, Res Inst, Skeletal Res Lab, Scarborough, ME 04074 USA
关键词
MINERAL DENSITY; FAT MASS; FRACTURES; WOMEN; MEN;
D O I
10.1038/nrendo.2009.249
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The paradigm that obesity at any age is protective against skeletal failure has been ingrained in clinical practice for several decades. A new study published in the Journal of Bone and Mineral Research challenges the basic framework of that tenet.
引用
收藏
页码:63 / 64
页数:2
相关论文
共 10 条
[1]  
DIMITRI P, J BONE MINER RES, DOI DOI 10.1359/JBMR.090823
[2]  
ELBAZ A, J CELL MOL MED, DOI DOI 10.1111/J.1582-49342009.00751.X
[3]   Reciprocal Relations of Subcutaneous and Visceral Fat to Bone Structure and Strength [J].
Gilsanz, Vicente ;
Chalfant, James ;
Mo, Ashley O. ;
Lee, David C. ;
Dorey, Frederick J. ;
Mittelman, Steven D. .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2009, 94 (09) :3387-3393
[4]   Bone mineral density in girls with forearm fractures [J].
Goulding, A ;
Cannan, R ;
Williams, SM ;
Gold, EJ ;
Taylor, RW ;
Lewis-Barned, NJ .
JOURNAL OF BONE AND MINERAL RESEARCH, 1998, 13 (01) :143-148
[5]  
Hsu YH, 2006, AM J CLIN NUTR, V83, P146
[6]   Fat mass is not beneficial to bone in adolescents and young adults [J].
Janicka, Agnieszka ;
Wren, Tishya A. L. ;
Sanchez, Monique M. ;
Dorey, Frederick ;
Kim, Paul S. ;
Mittelman, Steven D. ;
Gilsanz, Vicente .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2007, 92 (01) :143-147
[7]   Obese Japanese children have low bone mineral density after puberty [J].
Nagasaki, K ;
Kikuchi, T ;
Hiura, M ;
Uchiyama, M .
JOURNAL OF BONE AND MINERAL METABOLISM, 2004, 22 (04) :376-381
[8]   Minireview: Pref-1: Role in Adipogenesis and Mesenchymal Cell Fate [J].
Sul, Hei Sook .
MOLECULAR ENDOCRINOLOGY, 2009, 23 (11) :1717-1725
[9]   Associations between the metabolic syndrome and bone health in older men and women: the Rancho Bernardo Study [J].
von Muhlen, D. ;
Safii, S. ;
Jassal, S. K. ;
Svartberg, J. ;
Barrett-Connor, E. .
OSTEOPOROSIS INTERNATIONAL, 2007, 18 (10) :1337-1344
[10]  
World Health Organization Collaborating Centre for Metabolic Bone Diseases, WHO FRACT RISK ASS T