Total synthesis of natural products containing benzofuran rings

被引：141

作者：

Heravi, Majid M. ^{[1
]}

Zadsirjan, Vahideh ^{[1
]}

Hamidi, Hoda ^{[1
]}

Amiri, Parvin Hajiabbas Tabar ^{[1
]}

机构：

[1] Alzahra Univ, Dept Chem, Sch Sci, Tehran, Iran

来源：

RSC ADVANCES | 2017年 / 7卷 / 39期

基金：

新加坡国家研究基金会;

关键词：

FISCHER CARBENE COMPLEXES; 1ST TOTAL-SYNTHESIS; RESISTANT STAPHYLOCOCCUS-AUREUS; N-PHENYLPYRAZOLE DERIVATIVES; PALLADIUM-CATALYZED REACTION; PHOTO-FRIES REARRANGEMENT; CROSS-COUPLING REACTIONS; FUNGUS PHELLINUS-RIBIS; CARBON BOND FORMATION; ONE-POT SYNTHESIS;

D O I：

10.1039/c7ra03551a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Research on natural products containing benzofuran has remarkably increased during the past few decades. Newly isolated natural products with complex structures are being studied, characterized and screened for possible biological activities. Several of such compounds have exhibited various biological activities, thus their total syntheses have attracted much attention from synthetic organic chemists. In this review, we aim to highlight the origins, structures, biological potencies, and synthetic approaches of those natural products bearing at least one benzofuran in their complex structures. Furthermore, we especially focus on the step in which this key heterocycle is installed during the total synthesis of a natural product as the desired target.

引用

页码：24470 / 24521

页数：52

共 419 条

[11] Palladium-catalyzed reaction of o-ethynylphenols, o-((trimethylsilyl)ethynyl)phenyl acetates, and o-alkynylphenols with unsaturated triflates or halides: A route to 2-substituted-, 2,3-disubstituted-, and 2-substituted-3-acylbenzo[b]furans [J].