Three-Dimensional Holey-graphene for Simultaneous Sensing in Biological Fluids

被引：1
作者：
Jing, Aihua [1 ]
Xu, Qiong [1 ]
Feng, Wenpo [1 ]
Liang, Gaofeng [2 ]
机构：
[1] Henan Univ Sci & Technol, Sch Med Technol & Engn, Luoyang 471023, Peoples R China
[2] Henan Univ Sci & Technol, Med Coll, Luoyang 471023, Peoples R China
来源：
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE | 2019年 / 14卷 / 10期
基金：
中国国家自然科学基金;
关键词：
Three dimensional; Holey graphene; Electrochemical biosensor; Simultaneous detection; ASCORBIC-ACID; URIC-ACID; SENSITIVE DETERMINATION; DOPAMINE; ARCHITECTURES; HYBRID; NANOCOMPOSITES; TRYPTOPHAN; AEROGEL; FOAM;
D O I：
10.20964/2019.10.32
中图分类号：
O646 [电化学、电解、磁化学];
学科分类号：
081704 ;
摘要：
The quantification of ascorbic acid (AA), dopamine (DA), uric acid (UA) and tryptophan (Trp) has been an important area of research, as these molecules directly correspond to diagnosing and controlling diseases related to nerve and brain physiology. In our research, novel sensors of three-dimensional holey-graphene (3DHGO) were fabricated from holey graphene oxide with nano pores via a reduction method, and their morphology, structure and electrochemical performance were characterized with X-ray diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy, transmission electron microscopy and cyclic voltammograms. The proposed 3DHGO displayed excellent electron transport properties, high sensitivity and selectivity for the simultaneously detection of AA, DA, UA and Trp in healthy human serum and urine samples. This finding paves the way for the application of graphene as a biosensor for medical diagnosis.
引用
收藏
页码：9404 / 9414
页数：11
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