Update in status epilepticus

被引:4
作者
Santamarina, Estevo [1 ]
Abraira, Laura [1 ,2 ]
Toledo, Manuel [1 ]
机构
[1] Hosp Univ Vall dHebron, Serv Neurol, Unidad Epilepsia, Barcelona, Spain
[2] Univ Autonoma Barcelona, Barcelona, Spain
来源
MEDICINA CLINICA | 2019年 / 153卷 / 02期
关键词
Status epilepticus; Treatment; Antiepileptic drugs; REFRACTORY STATUS EPILEPTICUS; CONVULSIVE STATUS EPILEPTICUS; MORTALITY; METAANALYSIS; PROGNOSIS; BRIVARACETAM; LACOSAMIDE; THERAPIES; LORAZEPAM; DIAZEPAM;
D O I
10.1016/j.medcli.2019.01.013
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Status epilepticus (SE) is a neurological emergency that requires urgent antiepileptic therapies, and a rapid treatment of its cause. In recent years, its definition has been updated to adapt it to all types of SE; this update helps to standardise the treatment. The new definition is based on two times: point t1, after which the event will not spontaneously cease, and period t2, after which neuronal damage may appear. There are three lines of treatment: first, benzodiazepines; second, antiepileptic drugs; and third, intravenous anaesthetics. The application of the different lines of treatment raises still unanswered questions, since the prognosis also depends on the aetiology, age and duration. For this reason, different prognostic scales are being developed to help us to assess its evolution and in turn, adapt the aggressiveness of the treatment to each patient. (C) 2019 Elsevier Espana, S.L.U. All rights reserved.
引用
收藏
页码:70 / 77
页数:8
相关论文
共 45 条
[31]   Prognosis of status epilepticus (SE): Relationship between SE duration and subsequent development of epilepsy [J].
Santamarina, E. ;
Gonzalez, M. ;
Toledo, M. ;
Sueiras, M. ;
Guzman, L. ;
Rodriguez, N. ;
Quintana, M. ;
Mazuela, G. ;
Salas-Puig, X. .
EPILEPSY & BEHAVIOR, 2015, 49 :138-140
[32]   Intravenous lacosamide (LCM) in status epilepticus (SE): Weight-adjusted dose and efficacy [J].
Santamarina, Estevo ;
Gonzalez-Cuevas, Montserrat ;
Toledo, Manuel ;
Jimenez, Marta ;
Luis Becerra, Juan ;
Quilez, Alex ;
Suller, Ana ;
Mauri, J. A. ;
Fernandez, Angel ;
Marinas, Ainhoa ;
Quintana, Manuel ;
Salas Puig, Xavier .
EPILEPSY & BEHAVIOR, 2018, 84 :93-98
[33]   Emergency response to out-of-hospital status epilepticus A 10-year observational cohort study [J].
Semmlack, Saskia ;
Yeginsoy, Desiree ;
Spiegel, Rainer ;
Tisljar, Kai ;
Ruegg, Stephan ;
Marsch, Stephan ;
Sutter, Raoul .
NEUROLOGY, 2017, 89 (04) :376-384
[34]   The outcome of therapies in refractory and super-refractory convulsive status epilepticus and recommendations for therapy [J].
Shorvon, Simon ;
Ferlisi, Monica .
BRAIN, 2012, 135 :2314-2328
[35]   The treatment of super-refractory status epilepticus: a critical review of available therapies and a clinical treatment protocol [J].
Shorvon, Simon ;
Ferlisi, Monica .
BRAIN, 2011, 134 :2802-2818
[36]   Intramuscular versus Intravenous Therapy for Prehospital Status Epilepticus [J].
Silbergleit, Robert ;
Durkalski, Valerie ;
Lowenstein, Daniel ;
Conwit, Robin ;
Pancioli, Arthur ;
Palesch, Yuko ;
Barsan, William .
NEW ENGLAND JOURNAL OF MEDICINE, 2012, 366 (07) :591-600
[37]   Lacosamide in status epilepticus: Systematic review of current evidence [J].
Strzelczyk, Adam ;
Zoellner, Johann Philipp ;
Willems, Laurent M. ;
Jost, Julie ;
Paule, Esther ;
Schubert-Bast, Susanne ;
Rosenow, Felix ;
Bauer, Sebastian .
EPILEPSIA, 2017, 58 (06) :933-950
[38]   Treatment of refractory and super-refractory status epilepticus with brivaracetam: A cohort study from two German university hospitals [J].
Strzelczyk, Adam ;
Steinig, Isabel ;
Willems, Laurent M. ;
Reif, Philipp S. ;
Senft, Christian ;
Voss, Martin ;
Gaida, Bernadette ;
von Podewils, Felix ;
Rosenow, Felix .
EPILEPSY & BEHAVIOR, 2017, 70 :177-181
[39]   Anesthetic drugs in status epilepticus: Risk or rescue? A 6-year cohort study [J].
Sutter, Raoul ;
Marsch, Stephan ;
Fuhr, Peter ;
Kaplan, Peter W. ;
Rueegg, Stephan .
NEUROLOGY, 2014, 82 (08) :656-664
[40]   DETERMINANTS OF MORTALITY IN STATUS EPILEPTICUS [J].
TOWNE, AR ;
PELLOCK, JM ;
KO, DJ ;
DELORENZO, RJ .
EPILEPSIA, 1994, 35 (01) :27-34