Speaking of pharmacology - Who's afraid of ligand-macromolecule interactions in complex physiological systems?

被引：1

作者：

Shankley, Nigel ^{[1
]}

Cox, Bryan F.

Brunton, Laurence L.

机构：

[1] Johnson & Johnson Pharmaceut Res & Dev LLC, San Diego, CA 92121 USA

[2] Abbott Global Pharmaceut Res & Dev, Abbott Pk, IL 60064 USA

[3] Univ Calif San Diego, Sch Med, Dept Pharmacol, La Jolla, CA 92093 USA

来源：

MOLECULAR INTERVENTIONS | 2006年 / 6卷 / 06期

关键词：

D O I：

10.1124/mi.6.6.1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

[No abstract available]

引用

页码：296 / 299

页数：4

共 28 条

[1] Complexity and simplicity of ligand-macromolecule interactions: the energy landscape perspective
Verkhivker, GM
Bouzida, D
Gehlhaar, DK
Rejto, PA
Freer, ST
Rose, PW
CURRENT OPINION IN STRUCTURAL BIOLOGY, 2002, 12 (02) : 197 - 203
[2] Quantitative analysis of ligand-macromolecule interactions using differential dynamic quenching of the ligand fluorescence to monitor the binding
Jezewska, MJ
Bujalowski, W
BIOPHYSICAL CHEMISTRY, 1997, 64 (1-3) : 253 - 269
[3] SINGLE-CELL PARTITION ANALYSIS - A DIRECT FLUORESCENCE TECHNIQUE FOR EXAMINING LIGAND-MACROMOLECULE INTERACTIONS
GRAVES, DE
KRUGH, TR
ANALYTICAL BIOCHEMISTRY, 1983, 134 (01) : 73 - 81
[4] HYDROGEN-DEUTERIUM EXCHANGE ANALYSIS OF LIGAND-MACROMOLECULE INTERACTIONS - ETHIDIUM-DEOXYRIBONUCLEIC ACID SYSTEM
MANDAL, C
ENGLANDER, SW
KALLENBACH, NR
BIOCHEMISTRY, 1980, 19 (25) : 5819 - 5825
[5] THERMAL PERTURBATION TECHNIQUES IN CHARACTERIZING LIGAND-MACROMOLECULE INTERACTIONS - THEORY AND APPLICATION TO PROFLAVIN-ALPHA-CHYMOTRYPSIN SYSTEM
STURGILL, TW
JOHNSON, RE
BILTONEN, RL
BIOPOLYMERS, 1978, 17 (07) : 1773 - 1792
[6] MODEL FOR BINDING OF FLEXIBLE LIGANDS TO SURFACES OF PROTEINS AND OTHER MACROMOLECULES .2. PROPERTIES OF LIGAND-MACROMOLECULE SYSTEMS
LAIKEN, N
NEMETHY, G
JOURNAL OF PHYSICAL CHEMISTRY, 1970, 74 (25): : 4431 - &
[7] Anisotropic, polarizable molecular mechanics studies of inter- and intramoecular interactions and ligand-macromolecule complexes. A bottom-up strategy
Gresh, Nohad
Cisneros, G. Andres
Darden, Thomas A.
Piquemal, Jean-Philip
JOURNAL OF CHEMICAL THEORY AND COMPUTATION, 2007, 3 (06) : 1960 - 1986
[8] MOLECULAR SIEVE STUDIES OF INTERACTING PROTEIN SYSTEMS .7. DIRECT OPTICAL SCANNING METHOD FOR LIGAND-MACROMOLECULE BINDING STUDIES
BRUMBAUGH, EE
ACKERS, GK
ANALYTICAL BIOCHEMISTRY, 1971, 41 (02) : 543 - +
[9] Dissecting effects of complex mixtures - Who's afraid of informative priors?
Thomas, Duncan C.
Witte, John S.
Greenland, Sander
EPIDEMIOLOGY, 2007, 18 (02) : 186 - 190
[10] Who's afraid of coordinate systems? An essay on representation of spacetime structure
Wallace, David
STUDIES IN HISTORY AND PHILOSOPHY OF MODERN PHYSICS, 2019, 67 : 125 - 136

← 1 2 3 →