A novel carbazole-based mitochondria-targeted ratiometric fluorescent probe for bisulfite in living cells

被引：48
作者：
Wang, Gang [1 ]
Chen, Hao [2 ,3 ,4 ]
Chen, Xiuli [2 ,3 ,4 ]
Xie, Yongmei [2 ,3 ,4 ]
机构：
[1] Zunyi Med Coll, Zunyi, Guizhou Provinc, Peoples R China
[2] Sichuan Univ, West China Hosp, State Key Lab Biotherapy, Chengdu 610064, Sichuan Provinc, Peoples R China
[3] Sichuan Univ, West China Hosp, Ctr Canc, Chengdu 610064, Sichuan Provinc, Peoples R China
[4] Collaborat Innovat Ctr Biotherapy, Chengdu, Sichuan Provinc, Peoples R China
来源：
RSC ADVANCES | 2016年 / 6卷 / 22期
基金：
美国国家科学基金会;
关键词：
SULFUR-DIOXIDE DERIVATIVES; TURN-ON PROBE; SELECTIVE DETECTION; SO2; DERIVATIVES; REACTIVE PROBE; FAR-RED; SULFITE; RAT; CAPACITY; PATHWAY;
D O I：
10.1039/c5ra27805h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A novel mitochondria-targeted ratiometric fluorescent probe was developed via condensation of carbazole with two indolium units, which could realize the detection of bisulfite in a PBS buffer solution. The probe exhibited good mitochondrial location ability and could selectively respond to bisulfite among other sulfur-containing species in living cells.
引用
收藏
页码：18662 / 18666
页数：5
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