A novel carbazole-based mitochondria-targeted ratiometric fluorescent probe for bisulfite in living cells

被引：48
作者：
Wang, Gang [1 ]
Chen, Hao [2 ,3 ,4 ]
Chen, Xiuli [2 ,3 ,4 ]
Xie, Yongmei [2 ,3 ,4 ]
机构：
[1] Zunyi Med Coll, Zunyi, Guizhou Provinc, Peoples R China
[2] Sichuan Univ, West China Hosp, State Key Lab Biotherapy, Chengdu 610064, Sichuan Provinc, Peoples R China
[3] Sichuan Univ, West China Hosp, Ctr Canc, Chengdu 610064, Sichuan Provinc, Peoples R China
[4] Collaborat Innovat Ctr Biotherapy, Chengdu, Sichuan Provinc, Peoples R China
来源：
RSC ADVANCES | 2016年 / 6卷 / 22期
基金：
美国国家科学基金会;
关键词：
SULFUR-DIOXIDE DERIVATIVES; TURN-ON PROBE; SELECTIVE DETECTION; SO2; DERIVATIVES; REACTIVE PROBE; FAR-RED; SULFITE; RAT; CAPACITY; PATHWAY;
D O I：
10.1039/c5ra27805h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A novel mitochondria-targeted ratiometric fluorescent probe was developed via condensation of carbazole with two indolium units, which could realize the detection of bisulfite in a PBS buffer solution. The probe exhibited good mitochondrial location ability and could selectively respond to bisulfite among other sulfur-containing species in living cells.
引用
收藏
页码：18662 / 18666
页数：5
相关论文
共 46 条
[1]   Fluorescent indicators based on BODIPY [J].
Boens, Noel ;
Leen, Volker ;
Dehaen, Wim .
CHEMICAL SOCIETY REVIEWS, 2012, 41 (03) :1130-1172
[2]   Novel Coumarin-based Fluorescent Probe for Selective Detection of Bisulfite Anion in Water [J].
Chen Kangyu ;
Guo Yuan ;
Lu Zhenhuan ;
Yang Bingqin ;
Shi Zhen .
CHINESE JOURNAL OF CHEMISTRY, 2010, 28 (01) :55-60
[3]   A real-time colorimetric and ratiometric fluorescent probe for rapid detection of SO2 derivatives in living cells based on a near-infrared benzopyrylium dye [J].
Chen, Wenqiang ;
Liu, Xingjiang ;
Chen, Song ;
Song, Xiangzhi ;
Kang, Jian .
RSC ADVANCES, 2015, 5 (32) :25409-25415
[4]   Selective, Highly Sensitive Fluorescent Probe for the Detection of Sulfur Dioxide Derivatives in Aqueous and Biological Environments [J].
Chen, Wenqiang ;
Fang, Qian ;
Yang, Dalei ;
Zhang, Hongyan ;
Song, Xiangzhi ;
Foley, James .
ANALYTICAL CHEMISTRY, 2015, 87 (01) :609-616
[5]   "Reactive" probe for hydrogen sulfite: "turn-on" fluorescent sensing and bioimaging application [J].
Cheng, Xiaohong ;
Jia, Huizhen ;
Feng, Jun ;
Qin, Jingui ;
Li, Zhen .
JOURNAL OF MATERIALS CHEMISTRY B, 2013, 1 (33) :4110-4114
[6]   "Reactive" probe for hydrogen sulfite: Good ratiometric response and bioimaging application [J].
Cheng, Xiaohong ;
Jia, Huizhen ;
Feng, Jun ;
Qin, Jingui ;
Li, Zhen .
SENSORS AND ACTUATORS B-CHEMICAL, 2013, 184 :274-280
[7]   SURVEY OF SULFITES DETERMINED IN A VARIETY OF FOODS BY THE OPTIMIZED MONIER-WILLIAMS METHOD [J].
DANIELS, DH ;
JOE, FL ;
WARNER, CR ;
LONGFELLOW, SD ;
FAZIO, T ;
DIACHENKO, GW .
FOOD ADDITIVES AND CONTAMINANTS, 1992, 9 (04) :283-289
[8]   Endogenously generated sulfur dioxide and its vasorelaxant effect in rats [J].
Du, Shu-Xu ;
Jin, Hong-Fang ;
Bu, Ding-Fang ;
Zhao, Xia ;
Geng, Bin ;
Tang, Chao-Shu ;
Du, Jun-Bao .
ACTA PHARMACOLOGICA SINICA, 2008, 29 (08) :923-930
[9]   "Quinone-phenol" transduction activated excited-state intramolecular proton transfer: A new strategy toward ratiometric fluorescent probe for sulfite in living cells [J].
Geng, Linhua ;
Yang, Xiao-Feng ;
Zhong, Yaogang ;
Li, Zheng ;
Li, Hua .
DYES AND PIGMENTS, 2015, 120 :213-219
[10]   Effects of SO2 on Respiratory System of Adult Miyakejima Resident 2 Years after Returning to the Island [J].
Iwasawa, Satoko ;
Kikuchi, Yuriko ;
Nishiwaki, Yuji ;
Nakano, Makiko ;
Michikawa, Takehiro ;
Tsuboi, Tazuru ;
Tanaka, Shigeru ;
Uemura, Takamoto ;
Ishigami, Ai ;
Nakashima, Hiroshi ;
Takebayashi, Toru ;
Adachi, Mitsuru ;
Morikawa, Akihiro ;
Maruyama, Kouichi ;
Kudo, Shoji ;
Uchiyama, Iwao ;
Omae, Kazuyuki .
JOURNAL OF OCCUPATIONAL HEALTH, 2009, 51 (01) :38-47
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