Antimicrobial Activity of Cationic Gemini Surfactant Containing an Oxycarbonyl Group in the Lipophilic Portion against Gram-positive and Gram-negative Microorganisms

被引：13

作者：

Tatsumi, Taiga ^{[1
]}

Imai, Yoshitane ^{[2
]}

Kawaguchi, Kakuhiro ^{[2
]}

Miyano, Naoko ^{[3
]}

Ikeda, Isao ^{[4
]}

机构：

[1] Wakayama Univ, Fac Educ, Wakayama 6408510, Japan

[2] Kinki Univ, Fac Sci & Engn, Dept Appl Chem, Higashiosaka, Osaka 5778502, Japan

[3] Osaka Prefectural Inst Publ Hlth, Tennoji Ku, Osaka 5430026, Japan

[4] Osaka Univ, Fac Engn, Suita, Osaka 5650871, Japan

来源：

JOURNAL OF OLEO SCIENCE | 2014年 / 63卷 / 02期

关键词：

antimicrobial activity; biodegradability; cationic surfactant; Gemini surfactant; Gram-positive microorganism; Gram-negative microorganism; BUTENYLENE;

D O I：

10.5650/jos.ess13089

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

We evaluated the antimicrobial activities of a cationic Gemini surfactant, trans-1,4-bis [2-(alkanoyloxy)ethyldimethylammonio]-2-butene dichloride [II-m-2(t-butene)] and its derivatives against Gram-positive and Gram-negative microorganisms. The II-m-2(t-butene) compound was previously shown to have good surface activity and biodegradability. A dodecanoyloxy derivative (m = 12) of II-m-2(t-butene) showed excellent antimicrobial activity against Gram-positive Streptococcus aureus [minimum inhibitory concentration (MIC): 7.8 mu g/mL] and Gram-negative Escherichia coli (MIC: 31.2 mu g/mL).

引用

页码：137 / 140

页数：4

共 21 条

[1] Novel Gemini Cationic Surfactants Based on N, N-Dimethyl Fatty Hydrazide and 1,3-Dibromopropane: Synthesis, Evaluation of Surface and Antimicrobial Properties [J].