Pulsed Electron Double Resonance in Structural Studies of Spin-Labeled Nucleic Acids

被引：6
作者：
Fedorova, O. S. [1 ]
Tsvetkov, Yu D. [2 ]
机构：
[1] Russian Acad Sci, Siberian Branch, Inst Chem Biol & Fundamental Med, Novosibirsk 630090, Russia
[2] Russian Acad Sci, Siberian Branch, Inst Chem Kinet & Combust, Novosibirsk 630090, Russia
来源：
ACTA NATURAE | 2013年 / 5卷 / 01期
基金：
俄罗斯基础研究基金会;
关键词：
pulsed electron double resonance (PELDOR); spin-labels; DNA; RNA; oligonucleotides; NANOMETER DISTANCE MEASUREMENTS; TRICHOGIN GA-IV; EPR SPECTROSCOPY; CLICK CHEMISTRY; ABASIC SITES; DUPLEX DNA; PELDOR; RNA; DYNAMICS; ELDOR;
D O I：
10.32607/20758251-2013-5-1-9-32
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
This review deals with the application of the pulsed electron double resonance (PELDOR) method to studies of spin-labeled DNA and RNA with complicated spatial structures, such as tetramers, aptamers, riboswitches, and three- and four-way junctions. The use of this method for studying DNA damage sites is also described.
引用
收藏
页码：9 / 32
页数：24
相关论文
共 88 条
[1]   Long-Range Distance Determination in a DNA Model System inside Xenopus laevis Oocytes by In-Cell Spin-Label EPR [J].
Azarkh, Mykhailo ;
Okle, Oliver ;
Singh, Vijay ;
Seemann, Isabelle T. ;
Hartig, Joerg S. ;
Dietrich, Daniel R. ;
Drescher, Malte .
CHEMBIOCHEM, 2011, 12 (13) :1992-1995
[2]   Structure of a DNA glycosylase searching for lesions [J].
Banerjee, A ;
Santos, WL ;
Verdine, GL .
SCIENCE, 2006, 311 (5764) :1153-1157
[3]   A nucleoside that contains a rigid nitroxide spin label: A fluorophore in disguise [J].
Barhate, Nivrutti ;
Cekan, Pavol ;
Massey, Archna P. ;
Sigurdsson, Snorri Th. .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2007, 46 (15) :2655-2658
[4]  
Bender C., 2004, BIOL MAGNETIC RESONA, V21
[5]  
Berliner L., 2000, BIOL MAGNETIC RESONA, V19
[6]  
Berliner L., 1998, BIOL MAGNETIC RESONA, V14
[7]   Visualization of distance distribution from pulsed double electron-electron resonance data [J].
Bowman, MK ;
Maryasov, AG ;
Kim, N ;
DeRose, VJ .
APPLIED MAGNETIC RESONANCE, 2004, 26 (1-2) :23-39
[8]   Nanometer distance measurements in RNA using site-directed spin Labeling [J].
Cai, Qi ;
Kusnetzow, Ana Karin ;
Hideg, Kalman ;
Price, Eric A. ;
Haworth, Ian S. ;
Qin, Peter Z. .
BIOPHYSICAL JOURNAL, 2007, 93 (06) :2110-2117
[9]   Site-directed spin labeling measurements of nanometer distances in nucleic acids using a sequence-independent nitroxide probe [J].
Cai, Qi ;
Kusnetzow, Ana Karin ;
Hubbell, Wayne L. ;
Haworth, Ian S. ;
Gacho, Gian Paola C. ;
Van Eps, Ned ;
Hideg, Kalman ;
Chambers, Eric J. ;
Qin, Peter Z. .
NUCLEIC ACIDS RESEARCH, 2006, 34 (17) :4722-4730
[10]   The determination of pair distance distributions by pulsed ESR using Tikhonov regularization [J].
Chiang, YW ;
Borbat, PP ;
Freed, JH .
JOURNAL OF MAGNETIC RESONANCE, 2005, 172 (02) :279-295
123456789