Oligodendroglioma with Sarcomatous Transformation: Case Report and Literature Review

被引：0
|
作者：
Figueiredo, Goncalo Cerdeira [1 ]
Pinheiro, Celia Maria [1 ]
Calheiros, Alfredo Luis [1 ]
机构：
[1] Ctr Hosp Porto, Dept Neurosurg, P-4099001 Porto, Portugal
来源：
BRAZILIAN NEUROSURGERY-ARQUIVOS BRASILEIROS DE NEUROCIRURGIA | 2019年 / 38卷 / 02期
关键词：
oligodendroglioma; oligosarcoma; co-deletion; 1p/19q; spinal metastasis; GLIOSARCOMA; OLIGOSARCOMA;
D O I：
10.1055/s-0039-1685150
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
Oligodendrogliomas are infiltrative tumors of the central nervous system considered to be morphologically stable and to offer a better prognosis. Here, we describe the case of a 36-year-old man with an initial diagnosis of oligodendroglioma, World Health Organization (WHO) grade II, who presented transformation to a sarcomatous form, while maintaining the oligodendroglial component as well as the genetic characteristics of the initial tumor without having undergone any complementary treatments previously. Despite the favorable genetic characteristics, the tumor presented poor response to complementary treatments, and rapid progression, including spinal metastasis.
引用
收藏
页码：128 / 136
页数：9
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