What if higher plants lack a CDC25 phosphatase

被引:56
作者
Boudolf, Veronique [1 ]
Inze, Dirk [1 ]
De Veylder, Lieven [1 ]
机构
[1] Univ Ghent VIB, Dept Plant Syst Biol, B-9052 Ghent, Belgium
关键词
D O I
10.1016/j.tplants.2006.08.009
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Progression through the cell cycle is regulated by cyclin-dependent kinalses [CDKs). Plants possess a unique class of CDKs, designated B-type CDKs, but seem to lack a functional CDC25 phosphatase, which is a crucial activator of the onset of mitosis in non-plant species. Based on a striking number of functional parallels between the Arabidopsis thaliana CDKB1;1 and the Drosophila melanogaster CDC25 (string), we hypothesize that the acquisition of B-type CDKs and the disappearance of CDC25 in plants might have been associated; in these coupled events, the CDC25-controlled onset of mitosis might have been evolutionarily replaced by a B-type CDK-dominated pathway, eventually resulting in the loss of the CDC25 gene.
引用
收藏
页码:474 / 479
页数:6
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