Efficient elemental iodine catalyzed one-pot synthesis of 2,4,5-triarylimidazoles

被引：82

作者：

Kidwai, Mazaahir ^{[1
]}

Mothsra, Poonam ^{[1
]}

Bansal, Vikas ^{[1
]}

Goyal, Ritu ^{[1
]}

机构：

[1] Univ Delhi, Dept Chem, Green Chem Res Lab, New Delhi, India

来源：

MONATSHEFTE FUR CHEMIE | 2006年 / 137卷 / 09期

关键词：

elemental iodine; 2,4,5-triarylimidazoles; benzoin; ammonium acetate; aromatic aldehyde;

D O I：

10.1007/s00706-006-0518-9

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Elemental iodine is used as an efficient catalyst for the synthesis of 2,4,5-triarylimidazoles in excellent yields via condensation of benzoin, ammonium acetate, and aromatic aldehydes. This is a simple, one-pot, high yielding technique using cheap, non-toxic iodine in catalytic amounts.

引用

页码：1189 / 1194

页数：6

共 28 条

[1] One-pot synthesis of tetrasubstituted imidazoles catalyzed by zeolite HY and silica gel under microwave irradiation [J].

Balalaie, S ;

Arabanian, A .

GREEN CHEMISTRY, 2000, 2 (06) :274-276

[2] Stable carbenes [J].

Bourissou, D ;

Guerret, O ;

Gabbaï, FP ;

Bertrand, G .

CHEMICAL REVIEWS, 2000, 100 (01) :39-91

[3]

CLARK NG, 1975, TETRAHEDRON LETT, P2717

[4] Parallel synthesis of 1,2,4-trisubstituted imidazoles via N-alkyl-N-(β-keto)amides using a carbazate linker [J].

Cobb, JM ;

Grimster, N ;

Khan, N ;

Lai, JYQ ;

Payne, HJ ;

Payne, LJ ;

Raynham, T ;

Taylor, J .

TETRAHEDRON LETTERS, 2002, 43 (42) :7557-7560

[5] Experiments in the triazine and the glyoxaline series [J].

Cook, AH ;

Jones, DG .

JOURNAL OF THE CHEMICAL SOCIETY, 1941, :278-282

[6] The action of ammonia on benzil [J].

Davidson, D ;

Weiss, M ;

Jelling, M .

JOURNAL OF ORGANIC CHEMISTRY, 1937, 2 (04) :319-327

[7] Synthesis of substituted imidazoles via organocatalysis [J].

Frantz, DE ;

Morency, L ;

Soheili, A ;

Murry, JA ;

Grabowski, EJJ ;

Tillyer, RD .

ORGANIC LETTERS, 2004, 6 (05) :843-846

[8] ANTI-MYCOTIC IMIDAZOLES .4. SYNTHESIS AND ANTIFUNGAL ACTIVITY OF KETOCONAZOLE, A NEW POTENT ORALLY ACTIVE BROAD-SPECTRUM ANTIFUNGAL AGENT [J].

HEERES, J ;

BACKX, LJJ ;

MOSTMANS, JH ;

VANCUTSEM, J .

JOURNAL OF MEDICINAL CHEMISTRY, 1979, 22 (08) :1003-1005

[9]

JAPP FR, 1882, CHEM BER, V15, P1269

[10] 1-Aryl-4,6-diamino-1,2-dihydrotriazine as antimalarial agent: a new synthetic route [J].

Kidwai, M ;

Mothsra, P ;

Mohan, R ;

Biswas, S .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2005, 15 (04) :915-917

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