Clinical challenges with calcitonin-negative medullary thyroid carcinoma: three case report and a review of the literature

被引：4

作者：

Jingzhu, Z. ^{[1
,2
]}

Xiangqian, Z. ^{[1
,2
]}

Ming, G. ^{[1
,2
]}

Yi, P. ^{[1
,2
]}

Jiadong, C. ^{[1
,2
]}

Xinwei, Y. ^{[1
,2
]}

Xu Guangwei ^{[1
,2
]}

机构：

[1] Tianjin Med Univ Canc Inst & Hosp, Natl Clin Res Ctr Canc, Key Lab Canc Prevent & Therapy, Tianjin, Peoples R China

[2] Tianjins Clin Res Ctr Canc, Tianjin, Peoples R China

来源：

ANNALS OF THE ROYAL COLLEGE OF SURGEONS OF ENGLAND | 2022年 / 104卷 / 03期

基金：

中国国家自然科学基金;

关键词：

Medullary thyroid carcinoma; Calcitonin; Ct-negative MTC; Follow up; Prognosis; ASSOCIATION GUIDELINES; CANCER; DIAGNOSIS; MANAGEMENT;

D O I：

10.1308/rcsann.2020.7118

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Medullary thyroid carcinoma (MTC) is relatively rare, and has the main feature of calcitonin (Ct) secretion. However, a few cases of MTC with negative serum calcitonin have been reported in the literature, so the diagnosis and follow up of Ct-negative MTCs are still a challenge. Here we present three cases of Ct-negative MTCs, illustrating the rarity of the disease and challenges in managing it, together with a review of the literature of 39 MTCs with negative serum Ct.

引用

页码：221 / 230

页数：10

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