The Rising Problem of Multidrug-Resistant Organisms in Intensive Care Units

被引:9
作者
Riley, May Mei-Sheng [1 ]
机构
[1] Stanford Hlth Care, Stanford, CA USA
关键词
INFECTION-CONTROL; CLOSTRIDIUM-DIFFICILE; ICU; EPIDEMIOLOGY; TRANSMISSION; MULTICENTER; STRATEGIES; UNIVERSAL; MORTALITY; PATHOGENS;
D O I
10.4037/ccn2019773
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Because of antimicrobial overuse and misuse, the issue of multidrug-resistant organisms has been increasingly significant. Multidrug-resistant organism infection is of extreme concern in critical care patients. Infections with these organisms are difficult to treat because of the elevated rate of antimicrobial therapy failure. Such infections are linked to high mortality, poor prognosis, prolonged hospital stays, and increased medical expenses. Nineteen percent of patients with intensive care unit stays of greater than 24 hours acquire infections. Critically ill patients have risk factors that make them susceptible to infections. Critical care nurses must implement infection prevention interventions. Infection control strategies can be categorized as vertical or horizontal. Vertical approaches target a single pathogen; horizontal approaches are nonspecific. Infection control practice compliance is vital to prevent transmission of multidrug-resistant organisms through cross-contamination. This article discusses the severity of multidrug-resistant organism infection, risk factors, and infection prevention strategies in critical care settings.
引用
收藏
页码:48 / 55
页数:8
相关论文
共 34 条
  • [1] Host-Pathogen Interface: Progress in Understanding the Pathogenesis of Infection Due to Multidrug-Resistant Bacteria in the Intensive Care Unit
    Ahn, Danielle
    Prince, Alice
    [J]. JOURNAL OF INFECTIOUS DISEASES, 2017, 215 : S1 - S8
  • [2] Epidemiology of sepsis and infection in ICU patients from an international multicentre cohort study
    Alberti, C
    Brun-Buisson, C
    Burchardi, H
    Martin, C
    Goodman, S
    Artigas, A
    Sicignano, A
    Palazzo, M
    Moreno, R
    Boulmé, R
    Lepage, E
    Le Gall, JR
    [J]. INTENSIVE CARE MEDICINE, 2002, 28 (02) : 108 - 121
  • [3] Reemergence of gram-negative health care-associated bloodstream infections
    Albrecht, Svenja J.
    Fishman, Neil O.
    Kitchen, Jennifer
    Nachamkin, Irving
    Bilker, Warren B.
    Hoegg, Cindy
    Samel, Carol
    Barbagallo, Stephanie
    Arentzen, Judy
    Lautenbach, Ebbing
    [J]. ARCHIVES OF INTERNAL MEDICINE, 2006, 166 (12) : 1289 - 1294
  • [4] Anderson DJ, 2017, LANCET, V389, P805, DOI [10.1016/S0140-6736(16)31588-4, 10.1016/s0140-6736(16)31588-4]
  • [5] [Anonymous], 2013, Threat Report, P50
  • [6] Association of Professionals in Infection Control and Epidemiology, 2015, APIC IMPL GUID GUID
  • [7] Clostridium difficile in the ICU The Struggle Continues
    Bobo, Linda D.
    Dubberke, Erik R.
    Kollef, Marin
    [J]. CHEST, 2011, 140 (06) : 1643 - 1653
  • [8] The rising problem of antimicrobial resistance in the intensive care unit
    Brusselaers, Nele
    Vogelaers, Dirk
    Blot, Stijn
    [J]. ANNALS OF INTENSIVE CARE, 2011, 1
  • [9] Calfee DP, 2014, INFECT CONT HOSP EP, V35, P772, DOI [10.1086/676534, 10.1017/S0899823X00193882]
  • [10] Impact of vancomycin resistance on mortality in neutropenic patients with enterococcal bloodstream infection: a retrospective study
    Cho, Sung-Yeon
    Lee, Dong-Gun
    Choi, Su-Mi
    Kwon, Jae-Cheol
    Kim, Si-Hyun
    Choi, Jae-Ki
    Park, Sun Hee
    Park, Yeon-Joon
    Choi, Jung-Hyun
    Yoo, Jin-Hong
    [J]. BMC INFECTIOUS DISEASES, 2013, 13