Graves Disease After Thyroid Hormone Treatment for Thyroid Nodule
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Lai, Yun-Ju
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Taichung Vet Gen Hosp, Div Endocrinol & Metab, Dept Internal Med, Taichung 407, TaiwanTaichung Vet Gen Hosp, Div Endocrinol & Metab, Dept Internal Med, Taichung 407, Taiwan
Lai, Yun-Ju
[1
]
Lin, Shih-Yi
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Taichung Vet Gen Hosp, Div Endocrinol & Metab, Dept Internal Med, Taichung 407, TaiwanTaichung Vet Gen Hosp, Div Endocrinol & Metab, Dept Internal Med, Taichung 407, Taiwan
Lin, Shih-Yi
[1
]
Sheu, Wayne Huey-Herng
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Taichung Vet Gen Hosp, Div Endocrinol & Metab, Dept Internal Med, Taichung 407, TaiwanTaichung Vet Gen Hosp, Div Endocrinol & Metab, Dept Internal Med, Taichung 407, Taiwan
Sheu, Wayne Huey-Herng
[1
]
Lee, I-Te
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Taichung Vet Gen Hosp, Div Endocrinol & Metab, Dept Internal Med, Taichung 407, TaiwanTaichung Vet Gen Hosp, Div Endocrinol & Metab, Dept Internal Med, Taichung 407, Taiwan
Lee, I-Te
[1
]
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[1] Taichung Vet Gen Hosp, Div Endocrinol & Metab, Dept Internal Med, Taichung 407, Taiwan
Nodularity of the thyroid bland is extremely common, and suppression of thyroid-stimulating hormone secretion by thyroxin is one of the treatment options most often employed. However, exogenous thyroid hormone could be a precipitating factor for autoimmune hyperthyroidism. We studied a 39-year-old woman for a thyroid nodule found by sonogram. She had no palpable mass in the thyroid gland. She had no tremor. Thyroid function tests were normal. After 4 weeks of thyroxin 0.1-mg daily treatment. Graves disease was diagnosed by thyrotoxicosis and combined with diffuse increased radioactive iodine uptake in thyroid gland. The thyroxin was discontinued and the symptoms of thyrotoxicosis improved. Thyroid function test returned to normal, Physicians should be aware of the possibility of precipitating autoimmune hyperthyroidism with thyroxine suppressive therapy for thyroid nodules.