Application of heart rate variability to determine physiologic changes in hypothermic rats

被引：3
作者：
Bastille, AM
Matthew, CB
Gonzalez, RR
Sils, IV
Hoyt, RW
机构：
[1] USA, Res Inst Environm & Med, Thermal & Mt Med Div, Natick, MA 01760 USA
[2] USA, Res Inst Environm & Med, Biophys & Biomed Modeling Div, Natick, MA 01760 USA
来源：
JOURNAL OF THERMAL BIOLOGY | 2004年 / 29卷 / 4-5期
关键词：
hypothermia; physiological monitoring; heart rate; central control of cardiac frequency; autonomic nervous system; Rattus sp;
D O I：
10.1016/j.jtherbio.2004.02.007
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Time domain and power spectral density (PSD) analyses of ECG were used as indices of physiologic change in telemetry-equipped hypothermic rats. Anesthetized rats were either cooled (Hypo, Tc = 20degreesC) and then rewarmed or maintained normothermic (NC). Heart rate, blood pressure, interbeat interval (1131), normalized standard deviation (NSD) and PSD were determined. NSD in Hypo rats was significantly elevated at Tc = 30degreesC which was coincident with the transition from increasing to decreasing HR and BP during cooling. With no change in PSD at Tc = 30degreesC, the increased NSD suggests physiological events lacking an autonomic nervous system origin. Published by Elsevier Ltd.
引用
收藏
页码：237 / 243
页数：7
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