Functions of fungal melanin beyond virulence

被引：285

作者：

Cordero, Radames J. B. ^{[1
]}

Casadevall, Arturo ^{[1
]}

机构：

[1] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Mol Microbiol & Immunol, Baltimore, MD 21205 USA

来源：

FUNGAL BIOLOGY REVIEWS | 2017年 / 31卷 / 02期

基金：

美国国家卫生研究院;

关键词：

Black fungi; Energy harvest; Energy transducer; Free radical scavenging; Fungal melanin; Fungal melanization; Fungal pigments; Thermal melanism;

D O I：

10.1016/j.fbr.2016.12.003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Melanins are ancient biological pigments found in all kingdoms of life. In fungi, their role in microbial pathogenesis is well established; however, these complex biomolecules also confer upon fungal microorganisms the faculty to tolerate extreme environments such as the Earth's poles, the International Space Station and places contaminated by toxic metals and ionizing radiation. A remarkable property of melanin is its capacity to interact with a wide range of electromagnetic radiation frequencies, functioning as a protecting and energy harvesting pigment. Other roles of fungal melanin include scavenging of free radical, thermo-tolerance, metal ion sequestration, cell development, and mechanical chemical cellular strength. In this review, we explore the various functions ascribed to this biological pigment in fungi and its remarkable physicochemical properties. (C) 2017 British Mycological Society. Published by Elsevier Ltd. All rights reserved.

引用

页码：99 / 112

页数：14

共 265 条

[1]

A.-G.Mahmoud Yehia, 2004, Mycobiology, V32, P110

[2] Structural, electrical, electronic and optical properties of melanin films [J].