Measurement of charged particle yields from PMMA irradiated by a 220 MeV/u 12C beam

被引：64

作者：

Piersanti, L. ^{[1
,2
]}

Bellini, F. ^{[3
,4
]}

Bini, F. ^{[5
]}

Collamati, F. ^{[3
,4
]}

De Lucia, E. ^{[1
]}

Durante, M. ^{[6
]}

Faccini, R. ^{[3
,4
]}

Ferroni, F. ^{[3
,4
]}

Fiore, S. ^{[3
]}

Iarocci, E. ^{[1
,2
]}

La Tessa, C. ^{[6
]}

Marafini, M. ^{[3
,7
,8
]}

Mattei, I. ^{[1
,9
]}

Patera, V. ^{[2
,4
,7
,8
]}

Ortega, P. G. ^{[10
,11
]}

Sarti, A. ^{[1
,2
]}

Schuy, C. ^{[6
]}

Sciubba, A. ^{[2
,4
]}

Vanstalle, M. ^{[6
]}

Voena, C. ^{[3
,4
]}

机构：

[1] Ist Nazl Fis Nucl, Lab Nazl Frascati, I-00044 Frascati, Italy

[2] Univ Roma La Sapienza, Dipartimento Sci Base & Applicate Ingn, I-00185 Rome, Italy

[3] Univ Roma La Sapienza, Dipartimento Fis, I-00185 Rome, Italy

[4] Ist Nazl Fis Nucl, Sez Roma, Rome, Italy

[5] Univ Roma La Sapienza, Dipartimento Ingn Meccan & Aerosp, I-00185 Rome, Italy

[6] GSI Darmstadt, Darmstadt, Germany

[7] Museo Stor Fis, Rome, Italy

[8] Ctr Studi & Ric E Fermi, Rome, Italy

[9] Roma Tre Univ Roma, Dipartimento Matemat & Fis, Rome, Italy

[10] CERN, Geneva, Switzerland

[11] IFIC CSIC UV, Valencia, Spain

来源：

PHYSICS IN MEDICINE AND BIOLOGY | 2014年 / 59卷 / 07期

关键词：

drift chamber; LYSO; hadrontherapy; carbon ion beam; dose monitoring; PET MEASUREMENTS; ION;

D O I：

10.1088/0031-9155/59/7/1857

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The radiation used in hadrontherapy treatments interacts with the patient body producing secondary particles, either neutral or charged, that can be used for dose and Bragg peak monitoring and to provide a fast feedback on the treatment plans. Recent results obtained from the authors on simplified setups (mono-energetic primary beams interacting with homogeneous tissue like target) have already indicated the correlation that exists between the flux of these secondaries coming from the target (e.g. protons and photons) and the position of the primary beam Bragg peak. In this paper, the measurements of charged particle fluxes produced by the interaction of a 220 MeV/u carbon ion beam at GSI, Darmstadt, with a polymethyl methacrylate target are reported. The emission region of protons (p), deuterons (d) and tritons (t) has been characterized using a drift chamber while the particle time-of-flight, used to compute the kinetic energy spectra, was measured with a LYSO scintillator.The energy released in the LYSO crystal was used for particle identification purposes. The measurements were repeated with the setup at 60 degrees and 90 degrees with respect to the primary beam direction. The accuracy on the fragments emission profile reconstruction and its relationship with the Bragg peak position have been studied. Based on the acquired experimental evidence, a method to monitor the dose profile and the position of the Bragg peak inside the target is proposed.

引用

页码：1857 / 1872

页数：16

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