Biomarkers for Early Detection of Liver Cancer: Focus on Clinical Evaluation

被引:5
作者
Sun, Stella [1 ]
Day, Philip J. R. [2 ]
Lee, Nikki P. [1 ]
Luk, John M. [1 ]
机构
[1] Univ Hong Kong, Dept Surg, LKS Fac Med, Jockey Club Clin Res Ctr, Pokfulam, Hong Kong, Peoples R China
[2] Univ Manchester, Manchester Interdisciplinary Bioctr, Manchester, Lancs, England
关键词
Hepatocellular carcinoma; early cancer detection network; diagnostic imaging; serological biomarkers; EARLY HEPATOCELLULAR-CARCINOMA; ALPHA-FETOPROTEIN; TUMOR-MARKER; NEUROTROPHIC FACTOR; CHRONIC HEPATITIS; OVARIAN-CANCER; GROWTH-FACTOR; SERUM; CIRRHOSIS; DIAGNOSIS;
D O I
10.2174/092986609788167888
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This review summarises the screening methods from hepatic ultrasonography to serological biomarkers for early detection of liver cancer and focuses on evaluation of biomarkers ability. The development of novel biomarkers according to the 5-phase program defined by the Early Detection Research Network (EDRN) is also outlined in this review.
引用
收藏
页码:473 / 478
页数:6
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