Development of high-resolution detector module with depth of interaction identification for positron emission tomography

被引:16
作者
Niknejad, Tahereh [1 ]
Pizzichemi, Marco [2 ]
Stringhini, Gianluca [2 ,3 ]
Auffray, Etiennette [3 ]
Bugalho, Ricardo [1 ]
Da Silva, Jose Carlos [1 ]
Di Francesco, Agostino [1 ]
Ferramacho, Luis [4 ]
Lecoq, Paul [3 ]
Leong, Carlos [4 ]
Paganoni, Marco [2 ]
Rolo, Manuel [1 ,5 ]
Silva, Rui [1 ]
Silveira, Miguel [4 ]
Tavernier, Stefaan [4 ,6 ]
Varela, Joao [1 ,3 ]
Zorraquino, Carlos [7 ,8 ]
机构
[1] Lab Instrumentat & Expt Particles Phys, Lisbon, Portugal
[2] Univ Milano Bicocca, Milan, Italy
[3] CERN, Geneva, Switzerland
[4] PETsys Elect, Oeiras, Portugal
[5] INFN, Turin, Italy
[6] Vrije Univ Brussel, Brussels, Belgium
[7] Univ Politecn Madrid, Biomed Image Technol Lab, E-28040 Madrid, Spain
[8] Univ Politecn Madrid, CIBER BBN, E-28040 Madrid, Spain
关键词
Positron emission tomography; Positron emission mammography; Small animal PET; Depth of interaction; Time of flight; ARRAY;
D O I
10.1016/j.nima.2016.04.080
中图分类号
TH7 [仪器、仪表];
学科分类号
0804 ; 080401 ; 081102 ;
摘要
We have developed a Time-of-flight high resolution and commercially viable detector module for the application in small PET scanners. A new approach to depth of interaction (DOI) encoding with low complexity for a pixelated crystal array using a single side readout and 4-to-1 coupling between scintillators and photodetectors was investigated. In this method the DOI information is estimated using the light sharing technique. The detector module is a 1.53 x 1.53 x 15 mm(3) matrix of 8 x 8 LYSO scintillator with lateral surfaces optically depolished separated by reflective foils. The crystal array is optically coupled to 4 x 4 silicon photomultipliers (SiPM) array and readout by a high performance front-end ASIC with TDC capability (50 ps time binning). The results show an excellent crystal identification for all the scintillators in the matrix, a timing resolution of 530 ps, an average DOI resolution of 5.17 mm FWHM and an average energy resolution of 18.29% FWHM. (C) 2016 Elsevier B.V. All rights reserved.
引用
收藏
页码:684 / 688
页数:5
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