Levofloxacin-induced delirium

被引：19

作者：

Slobodin, Gleb ^{[1
,3
]}

Elias, Nizar ^{[1
,3
]}

Zaygraikin, Natalia ^{[1
]}

Sheikh-Ahmad, Muhammad ^{[1
]}

Sabetay, Sergiu ^{[2
]}

Weller, Boaz ^{[2
,3
]}

Odeh, Majed ^{[1
,3
]}

机构：

[1] Bnai Zion Med Ctr, Dept Internal Med A, IL-31063 Haifa, Israel

[2] Bnai Zion Med Ctr, Dept Neurol, IL-31063 Haifa, Israel

[3] Technion Israel Inst Technol, Bruce Rappaport Fac Med, IL-31096 Haifa, Israel

来源：

NEUROLOGICAL SCIENCES | 2009年 / 30卷 / 02期

关键词：

Quinolone; Fluoroquinolone; Levofloxacin; Delirium; CLARITHROMYCIN; OFLOXACIN;

D O I：

10.1007/s10072-009-0027-9

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

An 83-year-old man was admitted for right lower lobe pneumonia which did not improve after a 5-day outpatient treatment with amoxicillin/clavulinate and clarithromycin. An empiric treatment with levofloxacin was started with a significant improvement after 24 h of this treatment. On the third day of hospitalization, delirium developed, while the patient was afebrile and with normal blood oxygenation. Treatment with levofloxacin was stopped, and a complete resolution of the patient's delirium was observed 2 days later. To the best of our knowledge, this is the third case of levofloxacin-induced delirium described in the medical literature.

引用

页码：159 / 161

页数：3

共 15 条

[1] An approach to drug induced delirium in the elderly [J].

Alagiakrishnan, K ;

Wiens, CA .

POSTGRADUATE MEDICAL JOURNAL, 2004, 80 (945) :388-393

[2] Comparative tolerability of the newer fluoroquinolone antibacterials [J].

Ball, P ;

Mandell, L ;

Niki, Y ;

Tillotson, G .

DRUG SAFETY, 1999, 21 (05) :407-421

[3]

Brown T M, 2000, Semin Clin Neuropsychiatry, V5, P113

[4] Retrospective review of neurotoxicity induced by cefepime and ceftazidime [J].

Chow, KM ;

Szeto, CC ;

Hui, ACF ;

Wong, TYH ;

Li, PKT .

PHARMACOTHERAPY, 2003, 23 (03) :369-373

[5] Delirium induced by clarithromycin in a patient with community-acquired pneumonia [J].

de Vera, C. Vicente ;

Garcia, M. ;

Teixido, R. Pifarre ;

Barbe, F. .

EUROPEAN RESPIRATORY JOURNAL, 2006, 28 (03) :671-672

[6]

FENNIG S, 1992, J CLIN PSYCHIAT, V53, P137

[7] Levofloxacin-induced delirium:: Diagnostic considerations [J].

Fernandez-Torre, Jose L. .

CLINICAL NEUROLOGY AND NEUROSURGERY, 2006, 108 (06) :614-614

[8] Levofloxacin-induced delirium [J].

Hakko, E ;

Mete, B ;

Ozaras, R ;

Tabak, F ;

Ozturk, R ;

Mert, A .

CLINICAL NEUROLOGY AND NEUROSURGERY, 2005, 107 (02) :158-159

[9] Current concepts - Delirium in older persons [J].

Inouye, SK .

NEW ENGLAND JOURNAL OF MEDICINE, 2006, 354 (11) :1157-1165

[10] CIPROFLOXACIN-INDUCED COMPLEX PARTIAL STATUS EPILEPTICUS MANIFESTING AS AN ACUTE CONFUSIONAL STATE [J].

ISAACSON, SH ;

CARR, J ;

ROWAN, AJ .

NEUROLOGY, 1993, 43 (08) :1619-1621

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