Temperature-controlled release by changes in the secondary structure of peptides anchored onto mesoporous silica supports

被引：51

作者：

de la Torre, Cristina ^{[1
,2
,3
]}

Agostini, Alessandro ^{[1
,2
,3
]}

Mondragon, Laura ^{[1
,2
,3
]}

Orzaez, Mar ^{[4
,5
]}

Sancenon, Felix ^{[1
,2
,3
]}

Martinez-Manez, Ramon ^{[1
,2
,3
]}

Marcos, Maria D. ^{[1
,2
,3
]}

Amoros, Pedro ^{[6
]}

Perez-Paya, Enrique ^{[4
,5
]}

机构：

[1] Univ Valencia, Univ Politecn Valencia, Unidad Mixta, Ctr Reconocimiento Mol & Desarrollo Tecnol IDM, E-46003 Valencia, Spain

[2] Univ Politecn Valencia, Dept Quim, Valencia 46022, Spain

[3] CIBER Bioingn Biomat & Nanomed CIBER BBN, Zaragoza, Spain

[4] Ctr Invest Principe Felipe, Lab Peptidos & Prot, Valencia 46012, Spain

[5] IBV CSIC, Inst Biomed Valencia, Valencia 46010, Spain

[6] Univ Valencia, Inst Ciencia Mat ICMUV, Valencia 46071, Spain

来源：

CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 24期

关键词：

RESPONSIVE CONTROLLED-RELEASE; CHEMISTRY; VALVES;

D O I：

10.1039/c3cc49421g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Changes in the conformation of a peptide anchored onto the external surface of mesoporous silica nanoparticles have been used to design novel temperature-controlled delivery systems.

引用

页码：3184 / 3186

页数：3

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