Database resources of the national center for biotechnology information

被引:370
作者
Wheeler, David L. [1 ]
Barrett, Tanya [1 ]
Benson, Dennis A. [1 ]
Bryant, Stephen H. [1 ]
Canese, Kathi [1 ]
Chetvernin, Vyacheslav [1 ]
Church, Deanna M. [1 ]
DiCuccio, Michael [1 ]
Edgar, Ron [1 ]
Federhen, Scott [1 ]
Geer, Lewis Y. [1 ]
Helmberg, Wolfgang [1 ]
Kapustin, Yuri [1 ]
Kenton, David L. [1 ]
Khovayko, Oleg [1 ]
Lipman, David J. [1 ]
Madden, Thomas L. [1 ]
Maglott, Donna R. [1 ]
Ostell, James [1 ]
Pruitt, Kim D. [1 ]
Schuler, Gregory D. [1 ]
Schriml, Lynn M. [1 ]
Sequeira, Edwin [1 ]
Sherry, Stephen T. [1 ]
Sirotkin, Karl [1 ]
Souvorov, Alexandre [1 ]
Starchenko, Grigory [1 ]
Suzek, Tugba O. [1 ]
Tatusov, Roman [1 ]
Tatusova, Tatiana A. [1 ]
Wagner, Lukas [1 ]
Yaschenko, Eugene [1 ]
机构
[1] Natl Lib Med, Natl Ctr Biotechnol Informat, NIH, Bethesda, MD 20894 USA
基金
美国国家卫生研究院; 美国国家科学基金会;
关键词
D O I
10.1093/nar/gkj158
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In addition to maintaining the GenBank( R) nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for the data in GenBank and other biological data made available through NCBI's Web site. NCBI resources include Entrez, the Entrez Programming Utilities, MyNCBI, PubMed, PubMed Central, Entrez Gene, the NCBI Taxonomy Browser, BLAST, BLAST Link (BLink), Electronic PCR, OrfFinder, Spidey, Splign, RefSeq, UniGene, HomoloGene, ProtEST, dbMHC, dbSNP, Cancer Chromosomes, Entrez Genomes and related tools, the Map Viewer, Model Maker, Evidence Viewer, Clusters of Orthologous Groups, Retroviral Genotyping Tools, HIV-1, Human Protein Interaction Database, SAGEmap, Gene Expression Omnibus, Entrez Probe, GENSAT, Online Mendelian Inheritance in Man, Online Mendelian Inheritance in Animals, the Molecular Modeling Database, the Conserved Domain Database, the Conserved Domain Architecture Retrieval Tool and the PubChem suite of small molecule databases. Augmenting many of the Web applications are custom implementations of the BLAST program optimized to search specialized datasets. All of the resources can be accessed through the NCBI home page at: http://www.ncbi.nlm.nih.gov.
引用
收藏
页码:D173 / D180
页数:8
相关论文
共 31 条
[21]   Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements [J].
Schäffer, AA ;
Aravind, L ;
Madden, TL ;
Shavirin, S ;
Spouge, JL ;
Wolf, YI ;
Koonin, EV ;
Altschul, SF .
NUCLEIC ACIDS RESEARCH, 2001, 29 (14) :2994-3005
[22]  
Schuler GD, 1996, METHOD ENZYMOL, V266, P141
[23]   Pieces of the puzzle: expressed sequence tags and the catalog of human genes [J].
Schuler, GD .
JOURNAL OF MOLECULAR MEDICINE-JMM, 1997, 75 (10) :694-698
[24]   dbSNP: the NCBI database of genetic variation [J].
Sherry, ST ;
Ward, MH ;
Kholodov, M ;
Baker, J ;
Phan, L ;
Smigielski, EM ;
Sirotkin, K .
NUCLEIC ACIDS RESEARCH, 2001, 29 (01) :308-311
[25]   The Zebrafish Information Network (ZFIN): a resource for genetic, genomic and developmental research [J].
Sprague, J ;
Doerry, E ;
Douglas, S ;
Westerfield, M .
NUCLEIC ACIDS RESEARCH, 2001, 29 (01) :87-90
[26]   The COG database: an updated version includes eukaryotes [J].
Tatusov, RL ;
Fedorova, ND ;
Jackson, JD ;
Jacobs, AR ;
Kiryutin, B ;
Koonin, EV ;
Krylov, DM ;
Mazumder, R ;
Mekhedov, SL ;
Nikolskaya, AN ;
Rao, BS ;
Smirnov, S ;
Sverdlov, AV ;
Vasudevan, S ;
Wolf, YI ;
Yin, JJ ;
Natale, DA .
BMC BIOINFORMATICS, 2003, 4 (1)
[27]   Complete genomes in WWW Entrez: data representation and analysis [J].
Tatusova, TA ;
Karsch-Mizrachi, I ;
Ostell, JA .
BIOINFORMATICS, 1999, 15 (7-8) :536-543
[28]  
Tatusova TA, 1999, FEMS MICROBIOL LETT, V174, P247, DOI 10.1016/S0378-1097(99)00149-4
[29]   Cn3D: sequence and structure views for Entrez [J].
Wang, YL ;
Geer, LY ;
Chappey, C ;
Kans, JA ;
Bryant, SH .
TRENDS IN BIOCHEMICAL SCIENCES, 2000, 25 (06) :300-302
[30]  
WU CH, 2003, NUCLEIC ACIDS RES, V31, P45347