Competing Domino Processes: Path-Discriminating Ability of Epoxide Stereochemistry at the Angular Position

被引：10

作者：

Aquino, Maurizio ^{[1
]}

Safir, Imad ^{[1
]}

Elkhayat, Zobida ^{[1
]}

Gandara, Zoila ^{[1
]}

Perez, Manuel ^{[1
]}

Retailleau, Pascal ^{[1
]}

Arseniyadis, Simeon ^{[1
]}

机构：

[1] CNRS, Inst Chim Subst Nat, F-91198 Gif Sur Yvette, France

来源：

ORGANIC LETTERS | 2009年 / 11卷 / 16期

关键词：

MOLECULAR COMPLEXITY; POLYCYCLIC ETHERS; CYCLOADDITIONS; SUBSTITUTION; CYCLIZATION;

D O I：

10.1021/ol9013377

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Structurally different products can be reached selectively from unsaturated vicinal bicyclic diols, which differ only by the epoxide configuration at the angular position. It is possible to modify the regiochemical outcome of the domino process in such a way as to create a different pathway, [4 + 2] versus [4 + 3 + 2], and control product distribution by using the configuration bias. No previous example of a domino variant of the [4 + 3 + 2] process appears to have been documented.

引用

页码：3610 / 3613

页数：4

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