Synthesis of protected 3,5-dideoxy-3-C-azidomethyl-D-allofuranose, precursor of 3′,5′-C-modified nucleoside analogs

被引：0

作者：

Smits, H ^{[1
]}

Turks, M ^{[1
]}

Katkevica, D ^{[1
]}

Bizdena, E ^{[1
]}

机构：

[1] Riga Tech Univ, Fac Chem Technol, LV-1048 Riga, Latvia

来源：

CHEMISTRY OF NUCLEIC ACID COMPONENTS | 1999年 / 2卷

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

3,5-Dideoxy-3-C-azidomethyl-6-O-benzyl-1,2-O-diacetyl-(alpha, beta)-D-allofuranose has been prepared in eleven steps in 12% overall yield starting from 1,2;5,6-O-diisopropylideneglucose. This compound is useful intermediate for preparation of nucleoside analogs, as demonstrated by synthesis of corresponding uridine derivative.

引用

页码：39 / 42

页数：4

共 5 条

[1] SYNTHESIS AND ANTIVIRAL ACTIVITY OF 3'-DEOXY-3'-C-HYDROXYMETHYL NUCLEOSIDES [J].