Cinchona alkaloids in the asymmetric synthesis of 2-(phenylsulfanyl)aziridines

被引：37

作者：

Fioravanti, S ^{[1
]}

Mascia, MG ^{[1
]}

Pellacani, L ^{[1
]}

Tardella, PA ^{[1
]}

机构：

[1] Univ Roma La Sapienza, Dipartimento Chim, I-00185 Rome, Italy

来源：

TETRAHEDRON | 2004年 / 60卷 / 37期

关键词：

aza-Michael initiated ring closure (MIRC) reactions; aziridination; Cinchona alkaloids; heterogenous catalysis; chiral catalyst;

D O I：

10.1016/j.tet.2004.06.119

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Enantioselective aza-Michael initiated ring closure (MIRC) additions of ethyl nosyloxycarbamate to 2-(phenylsulfanyl)-2-cycloalkenones catalysed by Cinchona alkaloids were studied. The results suggest that the enantioselectivity obtained is influenced by the structure of the catalyst and the different amination conditions. Substrate ring size also plays an important role. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：8073 / 8077

页数：5

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