HLA-A, -B, -C,-DRB1 and-DQB1 allele and haplotype frequencies of 1463 umbilical cord blood units typed in high resolution from Bogota, Colombia

被引：11

作者：

Aurelio Paez-Gutierrez, Ivan ^{[1
]}

Guillermo Hernandez-Mejia, David ^{[1
]}

Vanegas, Diana ^{[1
]}

Camacho-Rodriguez, Bernardo ^{[2
]}

Maria Perdomo-Arciniegas, Ana ^{[1
]}

机构：

[1] IDCBIS, Cord Blood Bank, Cra 32 12-81, Bogota, Colombia

[2] IDCBIS, Gen Direct, Cra 32 12-81, Bogota, Colombia

来源：

HUMAN IMMUNOLOGY | 2019年 / 80卷 / 07期

关键词：

D O I：

10.1016/j.humimm.2019.03.006

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Allele and haplotype frequencies were calculated from 1463 umbilical cord blood (UCB) units, from Bogota (Colombia) donors, HLA-typed in high resolution. This is the first report using allele-level typed colombian samples of five HLA loci related to hematopoietic stem cell transplantation (HLA-A, -B, -C, -DRB1 and -DQB1). The most frequent haplotype found in our sample was A*24:02g similar to B*35:43g similar to C*01:02g similar to DRB1*04:07g DQB1.03:02g (4.14%). Our data are available at the Allele Frequencies Net Database under the code AFND3604.

引用

页码：425 / 426

页数：2

共 11 条

[1] [Anonymous], 2007, COL NAC MULT DIV ETN
[2] Advances in DNA sequencing technologies for high resolution HLA typing
Cereb, Nezih
Kim, Hwa Ran
Ryu, Jaejun
Yang, Soo Young
[J]. HUMAN IMMUNOLOGY, 2015, 76 (12) : 923 - 927
[3] DANE, 2005, CENS GEN 2005
[4] Arlequin suite ver 3.5: a new series of programs to perform population genetics analyses under Linux and Windows
Excoffier, Laurent
Lischer, Heidi E. L.
[J]. MOLECULAR ECOLOGY RESOURCES, 2010, 10 (03) : 564 - 567
[5] Identification of the novel HLA-DRB1 allele, DRB1*14:183, in a Colombian umbilical cord blood bank donor
Gonzalez-Acero, L. -X.
Camacho, B.
Perdomo-Arciniegas, A. M.
[J]. HLA, 2018, 92 (03) : 185 - 186
[6] New HLA-C alleles identified in two donors from the Colombian public umbilical cord blood bank
Gonzalez-Acero, Lorena X.
Camacho, Bernardo
Perdomo-Arciniegas, Ana M.
[J]. HLA, 2018, 92 (04) : 252 - 253
[7] Allele Frequencies Net Database: Improvements for storage of individual genotypes and analysis of existing data
Melos dos Santos, Eduardo Jose
McCabe, Antony
Gonzalez-Galarza, Faviel F.
Jones, Andrew R.
Middleton, Derek
[J]. HUMAN IMMUNOLOGY, 2016, 77 (03) : 238 - 248
[8] Ministerio de Relaciones Exteriores, 2018, INF GEN DIN MIGR COL
[9] Outlining the Ancestry Landscape of Colombian Admixed Populations
Ossa, Humberto
Aquino, Juliana
Pereira, Rui
Ibarra, Adriana
Ossa, Rafael H.
Adriana Perez, Luz
David Granda, Juan
Claudia Lattig, Maria
Groot, Helena
de Carvalho, Elizeu Fagundes
Gusmao, Leonor
[J]. PLOS ONE, 2016, 11 (10):
[10] Hapl-o-Mat: open-source software for HLA haplotype frequency estimation from ambiguous and heterogeneous data
Schaefer, Christian
Schmidt, Alexander H.
Sauter, Juergen
[J]. BMC BIOINFORMATICS, 2017, 18

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