Feasibility of dual-energy CBCT by spectral filtration of a dual-focus CNT x-ray source

被引:8
作者
Li, Boyuan [1 ]
Spronk, Derrek [2 ]
Luo, Yueting [2 ]
Puett, Connor [3 ]
Inscoe, Christina R. [1 ]
Tyndall, Donald A. [4 ]
Lee, Yueh Z. [5 ]
Lu, Jianping [1 ]
Zhou, Otto [1 ]
机构
[1] Univ N Carolina, Dept Phys & Astron, Chapel Hill, NC 27515 USA
[2] Univ N Carolina, Dept Appl Phys Sci, Chapel Hill, NC 27515 USA
[3] Univ N Carolina, Dept Biomed Engn, Chapel Hill, NC 27515 USA
[4] Univ N Carolina, Adams Sch Dent, Chapel Hill, NC 27515 USA
[5] Univ N Carolina, Dept Radiol, Chapel Hill, NC 27515 USA
关键词
CONE-BEAM CT; MAXILLOFACIAL RADIOLOGY; COMPUTED-TOMOGRAPHY; SYSTEM; NECK; HEAD;
D O I
10.1371/journal.pone.0262713
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Cone beam computed tomography (CBCT) is now widely used in dentistry and growing areas of medical imaging. The presence of strong metal artifacts is however a major concern of using CBCT especially in dentistry due to the presence of highly attenuating dental restorations, fixed appliances, and implants. Virtual monoenergetic images (VMIs) synthesized from dual energy CT (DECT) datasets are known to reduce metal artifacts. Although several techniques exist for DECT imaging, they in general come with significantly increased equipment cost and not available in dental clinics. The objectives of this study were to investigate the feasibility of developing a low-cost dual energy CBCT (DE-CBCT) by retrofitting a regular CBCT scanner with a carbon nanotube (CNT) x-ray source with dual focal spots and corresponding low-energy (LE) and high-energy (HE) spectral filters. A testbed with a CNT field emission x-ray source (NuRay Technology, Chang Zhou, China), a flat panel detector (Teledyne, Waterloo, Canada), and a rotating object stage was used for this feasibility study. Two distinct polychromatic x-ray spectra with the mean photon energies of 66.7keV and 86.3keV were produced at a fixed 120kVp x-ray tube voltage by using Al+Au and Al+Sn foils as the respective LE and HE filters attached to the exist window of the x-ray source. The HE filter attenuated the x-ray photons more than the LE filter. The calculated post-object air kerma rate of the HE beam was 31.7% of the LE beam. An anthropomorphic head phantom (RANDO, Nuclear Associates, Hicksville, NY) with metal beads was imaged using the testbed and the images were reconstructed using an iterative volumetric CT reconstruction algorithm. The VMIs were synthesized using an image-domain basis materials decomposition method with energy ranging from 30 to 150keV. The results were compared to the reconstructed images from a single energy clinical dental CBCT scanner (CS9300, Carestream Dental, Atlanta, GA). A significant reduction of the metal artifacts was observed in the VMI images synthesized at high energies compared to those from the same object imaged by the clinical dental CBCT scanner. The ability of the CNT x-ray source to generate the output needed to compensate the reduction of photon flux due to attenuation from the spectral filters and to maintain the CT imaging time was evaluated. The results demonstrated the feasibility of DE-CBCT imaging using the proposed approach. Metal artifact reduction was achieved in VMIs synthesized. The x-ray output needed for the proposed DE-CBCT can be generated by a fixed-anode CNT x-ray source.
引用
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页数:14
相关论文
共 35 条
[1]   Dedicated Cone-Beam CT System for Extremity Imaging [J].
Carrino, John A. ;
Al Muhit, Abdullah ;
Zbijewski, Wojciech ;
Thawait, Gaurav K. ;
Stayman, J. Webster ;
Packard, Nathan ;
Senn, Robert ;
Yang, Dong ;
Foos, David H. ;
Yorkston, John ;
Siewerdsen, Jeffrey H. .
RADIOLOGY, 2014, 270 (03) :816-824
[2]   Endodontic applications of cone-beam volumetric tomography [J].
Cotton, Taylor P. ;
Geisler, Todd M. ;
Holden, David T. ;
Schwartz, Scott A. ;
Schindler, William G. .
JOURNAL OF ENDODONTICS, 2007, 33 (09) :1121-1132
[3]   Advances in image-guided radiation therapy [J].
Dawson, Laura A. ;
Jaffray, David A. .
JOURNAL OF CLINICAL ONCOLOGY, 2007, 25 (08) :938-946
[4]   Initial Results of a Single-Source Dual-Energy Computed Tomography Technique Using a Split-Filter Assessment of Image Quality, Radiation Dose, and Accuracy of Dual-Energy Applications in an In Vitro and In Vivo Study [J].
Euler, Andre ;
Parakh, Anushri ;
Falkowski, Anna L. ;
Manneck, Sebastian ;
Dashti, David ;
Krauss, Bernhard ;
Szucs-Farkas, Zsolt ;
Schindera, Sebastian T. .
INVESTIGATIVE RADIOLOGY, 2016, 51 (08) :491-498
[5]   Single Scan dual energy Cone Beam CT Using a Rotating Filter [J].
Fang, Chengyijue ;
Xu, Gongming ;
Zhu, Lei .
MEDICAL IMAGING 2020: PHYSICS OF MEDICAL IMAGING, 2020, 11312
[6]   Cone beam computed tomography in dentomaxillofacial radiology: a two-decade overview [J].
Gaeta-Araujo, Hugo ;
Alzoubi, Tamara ;
Vasconcelos, Karla de Faria ;
Orhan, Kaan ;
Pauwels, Ruben ;
Casselman, Jan W. ;
Jacobs, Reinhilde .
DENTOMAXILLOFACIAL RADIOLOGY, 2020, 49 (08)
[7]   AIR Tools II: algebraic iterative reconstruction methods, improved implementation [J].
Hansen, Per Christian ;
Jorgensen, Jakob Sauer .
NUMERICAL ALGORITHMS, 2018, 79 (01) :107-137
[8]   Tungsten anode spectral model using interpolating cubic splines: Unfiltered x-ray spectra from 20 kV to 640 kV [J].
Hernandez, Andrew M. ;
Boone, John M. .
MEDICAL PHYSICS, 2014, 41 (04)
[9]   Artifact reduction from dental implants using virtual monoenergetic reconstructions from novel spectral detector CT [J].
Hokamp, Nils Grosse ;
Laukamp, K. R. ;
Lennartz, S. ;
Zopfs, D. ;
Abdullayev, N. ;
Neuhaus, V. F. ;
Maintz, D. ;
Borggrefe, J. .
EUROPEAN JOURNAL OF RADIOLOGY, 2018, 104 :136-142
[10]  
Inscoe C., 2020, Nanostructured Carbon Electron Emitters and Applications