The Impact of Bariatric Surgery on Polycystic Ovary Syndrome: a Systematic Review and Meta-analysis

被引：117

作者：

Skubleny, Daniel ^{[1
]}

Switzer, Noah J. ^{[2
]}

Gill, Richdeep S. ^{[2
,3
]}

Dykstra, Mark ^{[2
]}

Shi, Xinzhe ^{[3
]}

Sagle, Margaret A. ^{[4
]}

de Gara, Christopher ^{[2
,3
]}

Birch, Daniel W. ^{[2
,3
]}

Karmali, Shahzeer ^{[2
,3
]}

机构：

[1] Univ Alberta, Fac Med & Dent, Edmonton, AB, Canada

[2] Univ Alberta, Fac Med & Dent, Dept Surg, Edmonton, AB, Canada

[3] Royal Alexandra Hosp, Ctr Adv Minimally Invas Surg, Edmonton, AB, Canada

[4] Univ Alberta, Dept Obstet & Gynecol, Edmonton, AB, Canada

来源：

OBESITY SURGERY | 2016年 / 26卷 / 01期

关键词：

Bariatric surgery; Obesity; Polycystic ovary syndrome; SEVERELY OBESE ADOLESCENTS; Y GASTRIC BYPASS; WEIGHT-LOSS; WOMEN; INSULIN; OVERWEIGHT; REPRODUCTION; IMPROVEMENT; PREVALENCE; ENDOCRINE;

D O I：

10.1007/s11695-015-1902-5

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Bariatric surgery has been proven to be a successful management strategy for morbid obesity, but limited studies exist on its effect on polycystic ovary syndrome (PCOS). A comprehensive search of electronic databases was completed. Meta-analysis was performed on PCOS, hirsutism, and menstrual irregularity outcomes following bariatric surgery. Thirteen primary studies involving a total of 2130 female patients were identified. The incidence of PCOS preoperatively was 45.6 %, which significantly decreased to 6.8 % (P < 0.001) and 7.1 % (P < 0.0002) at 12-month follow-up and study endpoint, respectively. The incidences of preoperative menstrual irregularity and hirsutism both significantly decreased at 12-month and at study end follow-up. Bariatric surgery effectively attenuates PCOS and its clinical symptomatology including hirsutism and menstrual irregularity in severely obese women.

引用

页码：169 / 176

页数：8

共 45 条

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