Stiff Limb Syndrome: End of Spectrum or A Separate Entity?

被引：8

作者：

Misra, Usha K. ^{[1
]}

Maurya, Pradeep K. ^{[1
]}

Kalita, Jayantee ^{[1
]}

Gupta, Rakesh K. ^{[1
]}

机构：

[1] Sanjay Gandhi Postgrad Inst Med Sci, Dept Neurol & Radiodiag, Lucknow 226014, Uttar Pradesh, India

来源：

PAIN MEDICINE | 2009年 / 10卷 / 03期

关键词：

Stiffman; Stiff Limb; Stiff Person Syndrome; Diazepam; Treatment; GAD Antibody; PERSON SYNDROME; RIGIDITY;

D O I：

10.1111/j.1526-4637.2009.00578.x

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

Stiff-person syndrome is a rare disorder characterized by rigidity of axial or limb muscles with episodes of co-contraction of agonist and antagonist muscles during the spasms. In some patients axial or limb involvement may predominate and may have unusual manifestations. Case report. Tertiary care teaching hospital. A 42-year-old farmer presented with seasonal occurrence of hiccup and vomiting during summer months for the last 3 years. He had painful lower limb spasms lasting for 2-3 minutes every 10-15 minutes for the past 20 days. His neurological examination was normal, erythrocyte sedimentation rate (ESR) was 50 mm at 1st hour, and cerebrospinal fluid protein 78 mg/dL without pleocytosis. Radiograph of chest, abdominal ultrasound, and craniospinal magnetic resonance imaging were normal. The patient improved on diazepam. Our patient is a forme fruste of stiff person syndrome with hiccups and vomiting due to diaphragmatic spasm.

引用

页码：594 / 597

页数：4

共 16 条

[1] Review of 23 patients affected by the stiff man syndrome: Clinical subdivision into stiff trunk (man) syndrome, stiff limb syndrome, and progressive encephalomyelitis with rigidity [J].