Rhodium-catalyzed intramolecular annulation via C-H activation leading to fused tricyclic indole scaffolds

被引：63

作者：

Tao, Pengyu ^{[1
]}

Jia, Yanxing ^{[1
,2
]}

机构：

[1] Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China

[2] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 55期

基金：

中国国家自然科学基金;

关键词：

ACID; (+/-)-SEROTOBENINE; STEREOCHEMISTRY; HYDROARYLATION; COMBINATION; ALKENES; ALKYNES;

D O I：

10.1039/c4cc02947j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The rhodium(III)-catalyzed intramolecular annulation of alkyne-tethered acetanilides for the synthesis of fused tricyclic indole scaffolds via C-H activation has been developed, which has the potential for the synthesis of many indole alkaloids. This reaction proceeds under mild reaction conditions and with tolerance to a variety of functional groups.

引用

页码：7367 / 7370

页数：4

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