Dendritic nanoconjugate containing optimum folic acid for targeted intracellular curcumin delivery

被引：9

作者：

Fu, Yunlan ^{[1
]}

Gao, Xuli ^{[1
]}

Wan, Ying ^{[2
]}

Zhang, Ju ^{[3
,4
]}

Kong, Deling ^{[3
,4
]}

Wang, Zheng ^{[1
]}

Zhao, Yanjun ^{[1
]}

机构：

[1] Tianjin Univ, Sch Pharmaceut Sci & Technol, Tianjin Key Lab Modern Drug Delivery & High Effic, Tianjin 300072, Peoples R China

[2] Huazhong Univ Sci & Technol, Coll Life Sci & Technol, Wuhan 430074, Peoples R China

[3] Chinese Acad Med Sci, Inst Biomed Engn, Tianjin 300192, Peoples R China

[4] Peking Union Med Coll, Tianjin 300192, Peoples R China

来源：

RSC ADVANCES | 2014年 / 4卷 / 86期

基金：

中国国家自然科学基金;

关键词：

NANOMEDICINE; DENDRIMERS; CONJUGATE; DESIGN;

D O I：

10.1039/c4ra08315f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Based on surface-engineered poly(aminoamie) dendrimers, a novel type of targeted bifunctional nanoconjugate with optimum folic acid was designed to enhance the intracellular delivery of a highly pleiotropic active agent, curcumin.

引用

页码：46020 / 46023

页数：4

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