Association of nodular regenerative hyperplasia of the liver with porto-pulmonary hypertension in a patient with systemic lupus erythematosus

被引：12
作者：
Park, Y. W.
Woo, H.
Jeong, Y. Y.
Lee, J. H.
Park, J. J.
Lee, S. S.
机构：
[1] Chonnam Natl Univ Hosp, Dept Rheumatol, Kwangju 501757, South Korea
[2] Chonnam Natl Univ, Dept Diagnost Radiol, Kwangju, South Korea
[3] Chonnam Natl Univ Hosp, Dept Pathol, Kwangju, South Korea
来源：
LUPUS | 2006年 / 15卷 / 10期
关键词：
nodular regenerative hyperplasia; portal hypertension; pulmonary hypertension; systemic lupus erythematosus;
D O I：
10.1177/0961203306070976
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A 37-year old woman with systemic lupus erythematosus (SLE) complicated by pulmonary hypertension (PHT) was admitted to evaluate abnormal liver function. Radiological imaging study, including ultrasonography, computed tomography and magnetic resonance imaging and upper gastrointestinal endoscopy, revealed multiple hepatic nodules, hepatosplenomegaly and esophageal varices. Percutaneous needle liver biopsy showed non-cirrhotic hepatic nodules with hyperplastic hepatocytes surrounded by atrophic hepatocytes, confirming the diagnosis of nodular regenerative hyperplasia (NRH) associated with non-cirrhotic portal hypertension (PT). NRH of the liver is known to be a very rare hepatic manifestation in rheumatic diseases. This case shows the association of NRH with porto-pulmonary hypertension in SLE.
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收藏
页码：686 / 688
页数：3
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